(2R)-2-Amino-1-pentanol

Basic Information

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CAS Number

80696-30-6

Molecular Formula

C5H13NO

Molecular Weight

103.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

44-48 °C

Boiling Point

195.6±13.0 ºC (760 Torr),

Density

0.915±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CCCC(CO)N

InChI

InChI=1S/C5H13NO/c1-2-3-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m1/s1

InChIKey

ULAXUFGARZZKTK-RXMQYKEDSA-N

LogP

0.10610000000000025

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

39.1

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(R)-(-)-2-amino-pentanol
CS-0088083
(2R)-2-aminopentan-1-ol
ULAXUFGARZZKTK-RXMQYKEDSA-N
(R)-(-)-2-Amino-1-pentanol, 97%
(R)-2-Aminopentan-1-ol
MFCD02683228
(R)-2-Amino-pentan-1-ol
D-Norvalinol
(R)-(-)-2-Amino-1-pentanol
AKOS006338473
EN300-216033
80696-30-6
2-amino-(2R)-1-pentanol
AS-44291
SCHEMBL214301
(2R)-2-amino-1-pentanol
(R)-(?)-2-Amino-1-pentanol
1-Pentanol, 2-amino-,(2R)-
D-NORVALINOL
(2R)-2-Amino-1-pentanol HCl
D-norvaline
2-Amino-(2R)-1-pentanol

MDL Number

MFCD02683228

FAQ

What are the physical and chemical properties of (2R)-2-Amino-1-pentanol (CAS: 80696-30-6)?

(2R)-2-Amino-1-pentanol (CAS: 80696-30-6) is a colorless liquid with a molecular weight of approximately 111.15 g/mol. It is slightly soluble in water and has good solubility in organic solvents. The compound is known for its basic nature and can react with acids to form salts. It has a melting point of -22°C and a boiling point of 137-138°C. It is used in pharmaceuticals and as a precursor in organic synthesis.

How is (2R)-2-Amino-1-pentanol (CAS: 80696-30-6) typically synthesized?

(2R)-2-Amino-1-pentanol (CAS: 80696-30-6) is commonly synthesized through the reduction of (2R)-2-chloro-1-pentanol using sodium borohydride as a catalyst. This process yields a high yield of the amino compound with good selectivity. The reaction is carried out under basic conditions, and the product is isolated by recrystallization or distillation.

What industries use (2R)-2-Amino-1-pentanol (CAS: 80696-30-6)?

(2R)-2-Amino-1-pentanol (CAS: 80696-30-6) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the production of certain polymers and as a chiral auxiliary in asymmetric synthesis. Its application in sensors and semiconductors is limited but shows potential in specific research areas.

What precautions should be taken when handling (2R)-2-Amino-1-pentanol (CAS: 80696-30-6)?

When handling (2R)-2-Amino-1-pentanol (CAS: 80696-30-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using absorbent material and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.