Methyl (2S)-3-hydroxy-2-methylpropanoate

Basic Information

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CAS Number

80657-57-4

Molecular Formula

C5H10O3

Molecular Weight

118.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

74 °C/10 mmHg

Density

1.071 g/mL at 25 °C

Water Solubility

Insoluble in water. Soluble in methanol.

Refractive Index

n20/D 1.425(lit.)

SMILES

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CC(CO)C(=O)OC

InChI

InChI=1S/C5H10O3/c1-4(3-6)5(7)8-2/h4,6H,3H2,1-2H3/t4-/m0/s1

InChIKey

ATCCIZURPPEVIZ-BYPYZUCNSA-N

LogP

-0.21220000000000017

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

79.7

Safety Information

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Hazard Class

Class 3.2 Class 3.2

Synonyms & References

English

(S)-(+)-Methyl 3-hydroxy-2-methylpropionate
AMY14286
CS-W023098
(S)-(+)-methyl B-hydroxyisobutyrate
Methyl L-(+)-.beta.-hydroxyisobutyrate
Methyl (S)-(+)-2-methyl-3-hydroxypropionate
AKOS015850951
Methyl (S)-(+)-3-hydroxy-2-methyl-propionate
H0702
80657-57-4
EN300-85296
Methyl (S)-(+)-3-hydroxy-2-methylpropionate
(S)-( +)-3-hydroxy-2-methylpropionic acid methyl ester
methyl(s)-(+)-3-hydroxy-2-methylpropionate
(S)-(+)-methyl-3-hydroxy-2-methylpropionate
methyl (s)-3-hydroxy-2-methylpropionate
MFCD00064520
(+)-Methyl L-beta-hydroxyisobutyrate
A839959
Roche ester (S)
Methyl (S)-(+)-3-hydroxy-2-methylpropionate, 98%
(S)-(+)-3-Hydroxyisobutyric Acid Methyl Ester
(2S)-3-hydroxy-2-methyl-propionic acid methyl ester
AC-31279
(S)-3-hydroxy-2-methylpropionic acid methyl ester
(S)-Methyl3-hydroxy-2-methylpropanoate
AS-18926
(S)-3-Hydroxyisobutyric acid methyl ester
(S)-(+)methyl 3-hydroxy-2-methylpropionate
methyl 3-hydroxy-2-(S)-methylpropanoate
(S)-(+)-3-Hydroxy-2-methylpropionic Acid Methyl Ester

MDL Number

MFCD00064520

FAQ

What are the physical and chemical properties of Methyl (2S)-3-hydroxy-2-methylpropanoate (CAS: 80657-57-4)?

Methyl (2S)-3-hydroxy-2-methylpropanoate is a clear, colorless liquid with a molecular weight of approximately 120.16 g/mol. Its solubility in water is 10.3 g/L at 20°C. It is slightly unstable and can react with acids and bases. This compound is typically used in the synthesis of other organic compounds due to its reactivity and functional groups.

How is Methyl (2S)-3-hydroxy-2-methylpropanoate (CAS: 80657-57-4) typically synthesized?

Methyl (2S)-3-hydroxy-2-methylpropanoate is commonly synthesized via a multi-step process involving the reduction of 2,3-dimethyl-2-hydroxypropanoic acid. The reaction is usually catalyzed by a transition metal or a homogeneous catalyst, yielding a high yield of the desired product with good selectivity.

What industries use Methyl (2S)-3-hydroxy-2-methylpropanoate (CAS: 80657-57-4)?

Methyl (2S)-3-hydroxy-2-methylpropanoate is utilized in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also applied in the polymer industry as a monomer for the production of specific polymers. Additionally, it is used in the sensor and semiconductor industries for its chemical reactivity and specific functional groups.

What precautions should be taken when handling Methyl (2S)-3-hydroxy-2-methylpropanoate (CAS: 80657-57-4)?

When handling Methyl (2S)-3-hydroxy-2-methylpropanoate, it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. This compound should be handled in a fume hood due to its volatility and potential for reaction with moisture. In case of a spill, the area should be ventilated, and the spill should be cleaned up using appropriate absorbents. For detailed safety information, refer to the Safety Data Sheet (SDS).