Methyl (2S)-3-hydroxy-2-methylpropanoate(CAS: 80657-57-4)

Methyl (2S)-3-hydroxy-2-methylpropanoate is a clear, colorless liquid with a molecular weight of approximately 120.16 g/mol. Its solubility in water is 10.3 g/L at 20°C. It is slightly unstable and can react with acids and bases. This compound is typically used in the synthesis of other organic compounds due to its reactivity and functional groups.

Methyl (2S)-3-hydroxy-2-methylpropanoate is commonly synthesized via a multi-step process involving the reduction of 2,3-dimethyl-2-hydroxypropanoic acid. The reaction is usually catalyzed by a transition metal or a homogeneous catalyst, yielding a high yield of the desired product with good selectivity.

Methyl (2S)-3-hydroxy-2-methylpropanoate is utilized in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also applied in the polymer industry as a monomer for the production of specific polymers. Additionally, it is used in the sensor and semiconductor industries for its chemical reactivity and specific functional groups.

When handling Methyl (2S)-3-hydroxy-2-methylpropanoate, it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. This compound should be handled in a fume hood due to its volatility and potential for reaction with moisture. In case of a spill, the area should be ventilated, and the spill should be cleaned up using appropriate absorbents. For detailed safety information, refer to the Safety Data Sheet (SDS).