6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-chloro-8-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-chloro-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide | CAS No. 8027-33-6

6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-chloro-8-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-chloro-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide

Basic Information

CAS Number

8027-33-6

Molecular Formula

C88H92Cl6N6O6

Molecular Weight

1542.4 g/mol

AD

Basic Physical Properties

Melting Point

>56°

CC1=CC2=C(C=C1Cl)C3=C(C2)C(CCC3)C(=O)N.CC1=CC2=C(C=C1Cl)C3=C(C2)C(CCC3)C(=O)N.CC1=CC2=C(C=C1Cl)C3=C(C2)C(CCC3)C(=O)N.CC1=CC(=CC2=C1CC3=C2CCCC3C(=O)N)Cl.C1CC(C2=C(C1)C3=C(C2)C=CC(=C3)Cl)C(=O)N.C1CC(C2=C(C1)C3=C(C2)C=CC(=C3)Cl)C(=O)N

InChI

InChI=1S/4C15H16ClNO.2C14H14ClNO/c3*1-8-5-9-6-13-10(12(9)7-14(8)16)3-2-4-11(13)15(17)18;1-8-5-9(16)6-13-10-3-2-4-11(15(17)18)14(10)7-12(8)13;2*15-9-5-4-8-6-13-10(12(8)7-9)2-1-3-11(13)14(16)17/h3*5,7,11H,2-4,6H2,1H3,(H2,17,18);5-6,11H,2-4,7H2,1H3,(H2,17,18);2*4-5,7,11H,1-3,6H2,(H2,16,17)

InChIKey

VFCBJFRAECKYNC-UHFFFAOYSA-N

LogP

18.844279999999998

Topological Polar Surface Area

258.54 Ų

Hydrogen Bond Donor/Acceptor

12 / 12

Complexity

1180

Synonyms & References

English

  • 80748-21-6
  • 8027-33-6
  • Lanolin Alcohols
  • Wool alcohols
  • Alcohols,lanolin
  • LANOLIN ALCOHOL
  • AMERCHOL L 101
  • Cholesterol base H
  • Cordulan
  • Dusoline
  • Dusoran

FAQ

What are the physical and chemical properties of 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6)?

6-Chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6) is a crystalline compound with a molecular weight of approximately 275.04 g/mol. It has a melting point of about 100-102°C and is poorly soluble in water but soluble in organic solvents like methanol and ethyl acetate. This compound is known for its reactivity, particularly towards nucleophiles, and it undergoes substitution and addition reactions readily.

How is 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6) typically synthesized?

6-Chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6) is commonly synthesized through the condensation of 7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxylic acid and chloroacetic acid in the presence of a catalyst such as 4-Aminopyridine. The reaction typically proceeds with high selectivity and yields around 85-90%, depending on the conditions.

What industries use 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6)?

6-Chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6) is used in a variety of industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and polymer manufacturing, where it acts as a monomer. It also finds applications in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6)?

When handling 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide (CAS: 8027-33-6), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to minimize exposure. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.

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