N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

Basic Information

View in Editor

CAS Number

802539-81-7

Molecular Formula

C25H32N8O

Molecular Weight

460.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.33

SMILES

View in Editor

CC1(CC2=CN=C(N=C2C3=C1C(=NN3C)C(=O)NC)NC4=CC=C(C=C4)N5CCN(CC5)C)C

InChI

InChI=1S/C25H32N8O/c1-25(2)14-16-15-27-24(29-20(16)22-19(25)21(23(34)26-3)30-32(22)5)28-17-6-8-18(9-7-17)33-12-10-31(4)11-13-33/h6-9,15H,10-14H2,1-5H3,(H,26,34)(H,27,28,29)

InChIKey

RXZMYLDMFYNEIM-UHFFFAOYSA-N

LogP

2.5658000000000003

Topological Polar Surface Area

91.21 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

718

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

MMV676602
Milciclib; PHA 848125
HY-10424
NSC800792
pyrazolo[4,3-h]quinazoline-3-carboxamide, 28
Milciclib [INN]
NCGC00346673-01
Milciclib (PHA-848125)
Milciclib
BCP01918
SR-05000022565-1
HMS3656P21
SMR004700646
NCGC00346673-05
n,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1h-pyrazolo(4,3-h)quinazoline-3-carboxamide
EX-A2135
CCG-269340
AS-56203
SB16657
AC-35945
s2751
N,1,4,4-tetramethyl-8-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-5H-pyrazolo[4,5-h]quinazoline-3-carboxamide
N,1,4,4-Tetramethyl-8-{[4-(4-Methylpiperazin-1-Yl)phenyl]amino}-4,5-Dihydro-1h-Pyrazolo[4,3-H]quinazoline-3-Carboxamide
CS-0579
PHA848125
DTXSID80230186
D82291
BCPP000109
8-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid methylamide
Q27086363
1H-Pyrazolo(4,3-h)quinazoline-3-carboxamide, 4,5-dihydro-n,1,4,4-tetramethyl-8-((4-(4-methyl-1-piperazinyl)phenyl)amino)-

MDL Number

MFCD17169990

FAQ

What regulatory guidelines apply to N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7)?

N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) falls under the purview of GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for classification and labelling. It is also regulated by REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in the EU, requiring manufacturers and importers to register substances above a threshold of 1 tonne per year. FDA and EPA guidelines may apply based on its intended use, such as in pharmaceuticals or environmental applications.

Are there alternatives to N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) in synthesis?

Alternatives to N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) include structurally similar derivatives such as analogs with different substituents or isomers. Common alternative reagents in synthesis include other quinazolines, piperazines, and methylated compounds. These alternatives can offer similar biological activity or chemical properties with varying synthesis complexity.

What is the market or research trend for N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7)?

Research trends for N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) focus on its potential as a pharmaceutical compound, particularly in treating neurological disorders and as an anti-inflammatory agent. Market trends indicate growing interest in its pharmacological applications, with increasing focus on optimizing its synthesis and pharmacokinetics.

How should waste containing N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) be handled?

Waste containing N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) should be collected in appropriate containers and stored in a secure location away from ignition sources. Proper incineration or professional waste disposal methods should be utilized. Ensure that all handling and disposal procedures comply with local environmental protection regulations to prevent contamination of the environment.

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Compound Q&A

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N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide | CAS No. 802539-81-7

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Density

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

GHS Hazard Pictograms

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What regulatory guidelines apply to N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7)?

Are there alternatives to N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) in synthesis?

What is the market or research trend for N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7)?

How should waste containing N,1,4,4-Tetramethyl-8-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (CAS: 802539-81-7) be handled?

Related Compounds

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