2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine | CAS No. 80102-23-4
2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine
Basic Information
CAS Number
80102-23-4
Molecular Formula
C14H18ClNO4
Molecular Weight
299.75 g/mol
AD
Basic Physical Properties
Melting Point
94-98 °C
Specific Rotation
33 º (c=1,EtOH)
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-chlorophenyl)propanoic acid
- Boc-D-2-chlorophenylalanine (Boc-D-Phe(2-Cl)-OH)
- AC-5840
- N-TERT-BUTOXYCARBONYL-D-2-CHLORO PHENYLALANINE
- Boc-D-2-Chlorophe
- (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-chlorophenyl)propanoicacid
- Boc-D-Phe(2-Cl)-OH, >=98.0% (TLC)
- Boc-2-chloro-D-phenylalanine
- BOC-D-2-CLPHE
- AKOS016842830
- 80102-23-4
- PS-12130
- EN300-3367021
- (2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(2-chlorophenyl)propanoic acid
- MFCD00801056
- CS-W009959
- D-Phenylalanine, 2-chloro-N-[(1,1-dimethylethoxy)carbonyl]-
- SCHEMBL3485116
- N-(tert-butoxycarbonyl)-2-chloro-D-phenylalanine
- AM82736
- (2R)-3-(2-chlorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
- (R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-(2-CHLOROPHENYL)PROPANOIC ACID
- TUUQJNHCVFJMPU-LLVKDONJSA-N
- N-Boc-2-chloro-D-phenylalanine
- Boc-D-2-Chlorophenylalanine
- Boc-D-Phe(2-Cl)-OH
- BOC-D-Phe(2-Cl)-OH
- tert-Butoxycarbonyl-D-2-chlorophenylalanine
- 4-BroMophenethylaMine
- Boc-L-phe(2-Cl)-OH
- KSC916S4B
MDL Number
MFCD00801056
Customs Code
2924299090
FAQ
What are the physical and chemical properties of 2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 80102-23-4)?
2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine is a crystalline solid with a molecular weight of approximately 278.24 g/mol. It has a solubility of 0.28 mg/mL in water. The compound is moderately reactive, particularly with nucleophiles. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.
How is 2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 80102-23-4) typically synthesized?
2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine is synthesized via a multi-step process. Typically, the synthesis involves the protection of the phenylalanine hydroxyl group, followed by chlorination, and then deprotection. Common reagents include chlorinating agents and protecting groups. The yield is around 75-80%, and the selectivity is high.
What industries use 2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 80102-23-4)?
2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine is used in the pharmaceutical industry for the development of certain chiral intermediates and APIs. It is also utilized in the research and development of materials for sensors, semiconductors, and other specialized applications.
What precautions should be taken when handling 2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 80102-23-4)?
When handling 2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine (CAS: 80102-23-4), it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. Store the compound in a cool, dry place away from direct sunlight and flammable materials. Use a fume hood during handling. In case of spill, neutralize with an appropriate neutralizing agent and dispose of according to local regulations. Refer to the material safety data sheet (MSDS) for detailed information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
![2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine — ShangHaiMaiRuiErShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67ced3b52b2de6e8e95a6e52/67ced3b52b2de6e8e95a6e52-logo.webp){kind=logo}
![2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![2-Chloro-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-phenylalanine — Shanghai Titan Shareholding Technology Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdfa4757537e5c8069b08b/67cdfa4757537e5c8069b08b-logo.webp){kind=logo}