Epinastine hydrochloride interMediate product | CAS No. 80012-79-9

Epinastine hydrochloride interMediate product

Basic Information

CAS Number

80012-79-9

Molecular Formula

C19H20N2O4

Molecular Weight

340.37 g/mol

AD

Basic Physical Properties

C1C2=CC=CC=C2C(NC3=CC=CC=C31)CN.C(=CC(=O)O)C(=O)O

InChI

InChI=1S/C15H16N2.C4H4O4/c16-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)17-15;5-3(6)1-2-4(7)8/h1-8,15,17H,9-10,16H2;1-2H,(H,5,6)(H,7,8)

InChIKey

IUQYGXGUFNMQGL-UHFFFAOYSA-N

LogP

2.4145

Topological Polar Surface Area

112.64999999999999 Ų

Hydrogen Bond Donor/Acceptor

5 / 6

Complexity

372

Synonyms & References

English

  • Epinastine hydrochloride intermediate product
  • 6-Aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine (E)-2-butenedioate

MDL Number

MFCD11865145

FAQ

What are the physical and chemical properties of Epinastine hydrochloride intermediate product (CAS: 80012-79-9)?

Epinastine hydrochloride intermediate product (CAS: 80012-79-9) is typically a white crystalline solid with a molecular weight of approximately 452.7 g/mol. It is slightly soluble in water and alcohol. This intermediate product is highly reactive and requires careful handling due to its chemical nature.

How is Epinastine hydrochloride intermediate product (CAS: 80012-79-9) typically synthesized?

Epinastine hydrochloride intermediate product (CAS: 80012-79-9) is synthesized via a multi-step process involving protection of the amine group, introduction of the epoxide moiety, and subsequent acidification to form the hydrochloride salt. Commonly, this involves catalytic hydrogenation and selective oxidation reactions.

What industries use Epinastine hydrochloride intermediate product (CAS: 80012-79-9)?

Epinastine hydrochloride intermediate product (CAS: 80012-79-9) is primarily used in the pharmaceutical industry for the synthesis of epinastine, a histamine H1 receptor antagonist. It is also relevant in research and development for various drug formulations.

What precautions should be taken when handling Epinastine hydrochloride intermediate product (CAS: 80012-79-9)?

When handling Epinastine hydrochloride intermediate product (CAS: 80012-79-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Operations should be conducted in a well-ventilated fume hood. In case of spill, neutralize with a suitable base before cleaning up. Always consult the safety data sheet (SDS) for detailed guidance.

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