3-Amino-2-oxazolidinone

Basic Information

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CAS Number

80-65-9

Molecular Formula

C3H6N2O2

Molecular Weight

102.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

65-67 °C

Boiling Point

167.2°C at 760 mmHg

Density

1.179

Flash Point

54.9°C

Refractive Index

1.517

SMILES

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NN1CCOC1=O

InChI

InChI=1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2

InChIKey

KYCJNIUHWNJNCT-UHFFFAOYSA-N

LogP

-0.6877000000000002

Topological Polar Surface Area

55.559999999999995 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

92.9

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Oxazolidinone,3-amino-
3-Amino-2-Oxazolidinone
AOZ
3-amino-1,3-oxazolidin-2-one
3-aminooxazolidin-2-one
2-Oxazolidinone,3-amino
3-Amino-2-oxazolidone
3-Amino-oxazolidin-2-on
3-amino-oxazolidin-2-one
N-amino-2-oxazolidinone
NSC 111187
NSC 196570
NSC 38250
2-Oxazolidinone, 3-amino-
NSC38250
VJ7HE86A15
KYCJNIUHWNJNCT-UHFFFAOYSA-N
3-Amino-2-oxazolidinone (AOZ)
3-amino oxazolidinone
3-Amino-1,3-oxazolidin-2-one #
NSC196570
NSC111187
VZ34984
AS

MDL Number

MFCD00020871

FAQ

What are the physical and chemical properties of 3-Amino-2-oxazolidinone (CAS: 80-65-9)?

3-Amino-2-oxazolidinone (CAS: 80-65-9) is a white crystalline solid with a molecular weight of approximately 117.14 g/mol. It has a solubility of about 2.5 g/L in water and is slightly soluble in organic solvents. This compound is known for its reactivity in amine and carboxylic acid functionalities. It is also stable under normal conditions but reacts with strong acids and bases.

How is 3-Amino-2-oxazolidinone (CAS: 80-65-9) typically synthesized?

3-Amino-2-oxazolidinone (CAS: 80-65-9) is typically synthesized via the amidation of 2-oxazolidinone with an amino-containing compound. Commonly used catalysts include strong acids like hydrochloric acid. The reaction is carried out under mild conditions, and the yield can be improved by optimizing the reaction time and temperature. This method offers good selectivity and reproducibility.

What industries use 3-Amino-2-oxazolidinone (CAS: 80-65-9)?

3-Amino-2-oxazolidinone (CAS: 80-65-9) is used in various industries. It is primarily utilized in pharmaceuticals for the synthesis of drugs and intermediates. Additionally, it finds applications in the production of polymers, sensors, and semiconductors due to its unique chemical properties and reactivity.

What precautions should be taken when handling 3-Amino-2-oxazolidinone (CAS: 80-65-9)?

When handling 3-Amino-2-oxazolidinone (CAS: 80-65-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. Store the compound in a cool, dry place away from strong acids and bases. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.