1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt) | CAS No. 799268-59-0

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)

Basic Information

CAS Number

799268-59-0

Molecular Formula

C47H88NO19P3

Molecular Weight

1064.13 g/mol

AD

Basic Physical Properties

P(=O)(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)O[C@@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(=O)(O)O)OP(=O)(O)O)O)O.N

InChI

1S/C47H85O19P3.H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)63-39(37-61-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-62-69(59,60)66-45-42(50)43(51)46(64-67(53,54)55)47(44(45)52)65-68(56,57)58;/h11,13,17,19,22,24,28,30,39,42-47,50-52H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,59,60)(H2,53,54,55)(H2,56,57,58);1H3/b13-11-,19-17-,24-22-,30-28-;/t39-,42-,43+,44+,45-,46-,47-;/m1./s1

InChIKey

MDNBPTGUKOPWCG-RDBJESJXSA-N

LogP

9.5649

Topological Polar Surface Area

337.57 Ų

Hydrogen Bond Donor/Acceptor

11 / 20

Complexity

1630

Synonyms & References

English

  • 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)
  • 18:0-20:4 PI(4
  • 1-STEAROYL-2-ARACHIDONOYL-SN-GLYCERO-3-PHOSPHO-(1'-MYO-INOSITOL-4',5'-BISPHOSPHATE) (AMMONIUM SALT)
  • 5)P2
  • 18:0-20:4 PI(4,5)P2
  • CID 145710457
  • 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-[phosphoinositol-4,5-bisphosphate] (ammonium salt); PIP2[4′,5′](18:0/20:4(5Z,8Z,11Z,14Z))

FAQ

What are the physical and chemical properties of 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (CAS: 799268-59-0)?

The compound is a phospholipid with a complex structure. It has a crystalline form with a specific molecular weight of approximately 1000 Da. Its solubility is low in water but better in organic solvents. It is reactive and susceptible to hydrolysis and oxidation under certain conditions. The compound is stable under neutral pH and moderate temperatures.

How is 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (CAS: 799268-59-0) typically synthesized?

The compound is synthesized through a multi-step process involving esterification and phosphorylation reactions. Commonly, it is synthesized using a transesterification reaction between a stearoyl and arachidonoyl donor and glycerol, followed by phosphorylation using Myo-inositol-4,5-bisphosphate. The synthesis is typically catalyzed by lipases and requires careful control of reaction conditions to achieve high yield and selectivity.

What industries use 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (CAS: 799268-59-0)?

This compound is primarily used in pharmaceutical and biochemical research, as a model lipid for studying biological membranes and signaling pathways. It is also used in the development of novel drug delivery systems and as a component in certain sensors and semiconductors.

What precautions should be taken when handling 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (CAS: 799268-59-0)?

When handling this compound, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. The Material Safety Data Sheet (MSDS) should be consulted for detailed safety information and emergency procedures.

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