Compound Q&A

How is 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (CAS: 799268-59-0) typically synthesized?

Answer

1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)
The compound is synthesized through a multi-step process involving esterification and phosphorylation reactions. Commonly, it is synthesized using a transesterification reaction between a stearoyl and arachidonoyl donor and glycerol, followed by phosphorylation using Myo-inositol-4,5-bisphosphate. The synthesis is typically catalyzed by lipases and requires careful control of reaction conditions to achieve high yield and selectivity.

About

English Name 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)
Molecular Formula C47H88NO19P3
Molecular Weight 1064.13 g/mol
SMILES P(=O)(O)(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)O[C@@H]1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(=O)(O)O)OP(=O)(O)O)O)O.N
InChIKey MDNBPTGUKOPWCG-RDBJESJXSA-N
Last Updated: 2026-03-22 14:59

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