Levonorgestrel (D-(-)-Norgestrel) (Etonogestrel EP Impurity G)

Basic Information

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CAS Number

797-63-7

Molecular Formula

C20H30O2

Molecular Weight

302.46 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

234.0 to 238.0 deg-C

Boiling Point

459.1°C at 760 mmHg

Density

1.0697 (rough estimate)

Flash Point

195.4 °C

Refractive Index

1.4900 (estimate)

Specific Rotation

-31 ~ -34° (c=1, CHCl3)

SMILES

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CC[C@@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]2CC[C@@]1(O)C#C

InChI

InChI=1S/C20H30O2/c1-3-20-11-8-16-15-7-5-14(21)12-13(15)4-6-17(16)18(20)9-10-19(20,2)22/h12,15-18,22H,3-11H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1

InChIKey

SLAJADUWNNAURO-XGXHKTLJSA-N

LogP

4.269300000000004

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

609

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

Levonorgestrel
13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one
13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one
13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1
17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one
17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one
17-ethynyl-18-methyl-19-nortestosteron
17-ethynyl-18-methyl-19-nortestosterone
18-methyl-17-alpha-ethynyl-19-nortestosterone
(-)-Norgestrel
[18,19-Dinorpregn-4-en-20-yn-3-one-13-ethyl-17-hydroxy-,(17.α.)-(-)-]
D-(-)-Norgestrel
D(−)-Norgestrel
D-Norgestrel
(-)-18,19-Dinor-13β-ethyl-17β-hydroxy-4-pregnen-20-yn-3-one
(-)-17α-Ethynyl-18-methyl-19-nortestosterone
(-)-Levonorgestrel
D(-)-13beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one
norgestrel
Microval
Levonova
Postinor
Mirena
Ovrette
Neogest
Jadelle
Plan B
NORPLANT
Norplant 2
Microlution
Follistrel

MDL Number

MFCD00199013

FAQ

What is Levonorgestrel (D-(-)-Norgestrel) (CAS: 797-63-7)?

Levonorgestrel (D-(-)-Norgestrel), with the CAS number 797-63-7, is a synthetic progestin used in hormonal contraceptives. It is a derivative of norgestrel and has the chemical formula C21H28O2. The compound is characterized by its potency as a progesterone receptor agonist and its ability to inhibit ovulation, making it a key component in emergency contraceptive pills and other hormonal therapies.

What are the main uses of Levonorgestrel (D-(-)-Norgestrel) (CAS: 797-63-7)?

Levonorgestrel (CAS: 797-63-7) is primarily used in pharmaceuticals as a contraceptive agent. It is also employed in research for studying hormonal effects and in the production of other progestin-based medications. Its applications include emergency contraception, hormone replacement therapy, and as an impurity in drug development processes.

Is Levonorgestrel (D-(-)-Norgestrel) (CAS: 797-63-7) safe?

Levonorgestrel (CAS: 797-63-7) is generally considered safe when used as directed in medical applications. However, it may cause side effects such as nausea, headaches, or changes in menstrual patterns. Proper handling and adherence to safety guidelines are essential, particularly during storage and administration to ensure its efficacy and minimize risks.

How should Levonorgestrel (D-(-)-Norgestrel) (CAS: 797-63-7) be stored?

Levonorgestrel (CAS: 797-63-7) should be stored in a cool, dry place away from light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and in airtight containers to maintain stability. Avoid exposure to moisture and direct sunlight to preserve its chemical integrity and potency.