3-chloro-5-(trifluoromethyl)pyridin-2-amine

Basic Information

View in Editor

CAS Number

79456-26-1

Molecular Formula

C6H4ClF3N2

Molecular Weight

196.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

94.0 to 97.0 deg-C

Boiling Point

205 ºC

Density

1.4650 (estimate)

Flash Point

55-60℃

SMILES

View in Editor

C1=C(C=NC(=C1Cl)N)C(F)(F)F

InChI

InChI=1S/C6H4ClF3N2/c7-4-1-3(6(8,9)10)2-12-5(4)11/h1-2H,(H2,11,12)

InChIKey

WXNPZQIRDCDLJD-UHFFFAOYSA-N

LogP

2.3360000000000003

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

161

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H412

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Sensitive to moisture

Synonyms & References

English

SR-01000597237
2-?Amino-?3-?chloro-?5-?trifluoromethylpyrid?ine
2-Amino-3-chloro-5-(trifluoromethyl)pyridine
2-Amino-3-chloro-5-trifluoropyridine
2-Amino-3-chloro-5-(trifluoromethyl)pyridine, 97%
SR-01000597237-1
BDBM626073
SCHEMBL119730
2-AMINO-3-CHLORO-5-(TRIFLOROMETHYL)PYRIDINE
A1157
3-Chloro-5-(trifluoromethyl)pyridin-2-amine
AM20070272
FT-0656032
3-Chloro-5-(trifluoromethyl)-2-pyridinamine
3-Chloro-5-trifluoromethyl-2-pyridylamine
DTXSID00345807
71456-26-3
3-chloro-4,5,6-trifluoropyridin-2-amine
EC 401-670-0
WXNPZQIRDCDLJD-UHFFFAOYSA-
3-Chloro-5-(trifluoromethyl)-2-pyridinylamine #
2-amino-3-chloro-5-trifluoromethyl pyridine
A9910
2-Amino-3-chloro-5-trifluoromethylpyridine
3-Pyridinamine,2-fluoro-5-(trifluoromethyl)-
SY004773
Q-101470
2-amino-3-chloro- 5-trifluoromethylpyridine
Z104472970
FT3V8L4S3Y
3-chloro-5-(trifluoromethyl)-2-aminopyridine

MDL Number

MFCD00042154

Customs Code

2933399090

FAQ

What is 3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1)?

3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) is a synthetic organic compound featuring a pyridine ring substituted with a chloro group at position 3, a trifluoromethyl group at position 5, and an amino group at position 2. It is a white crystalline solid with moderate solubility in polar solvents. Its chemical formula is C7H6ClF3N, and it is known for its stability under normal conditions, making it a key intermediate in various chemical applications.

What are the main uses of 3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1)?

3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) is primarily used in pharmaceutical research as a building block for drug development. It also finds applications in agrochemicals, specialty chemicals, and materials science due to its unique functional groups. Its trifluoromethyl substitution enhances chemical stability, while the amino group allows for versatile reactivity in synthetic processes.

Is 3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) safe?

3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) requires careful handling due to potential toxicity. It may irritate skin, eyes, and respiratory systems, so protective measures like gloves, goggles, and ventilation are essential. Safety standards recommend following OSHA and CDC guidelines, and it should be stored in a controlled environment to minimize risks. Always consult safety data sheets (SDS) for detailed information.

How should 3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) be stored?

3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS: 79456-26-1) should be stored in a cool, dry, and well-ventilated area at temperatures below 25°C. It is sensitive to moisture and light, so keep it in a sealed, light-resistant container. Ensure storage away from incompatible substances and maintain proper labeling to ensure stability and safety compliance.