7-Amino-3-vinyl-3-cephem-4-carboxylic Acid

Basic Information

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CAS Number

79349-82-9

Molecular Formula

C9H10N2O3S

Molecular Weight

226.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

240-252°C (dec.)

Boiling Point

540.7°C at 760 mmHg

SMILES

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C=CC1=C(N2C(C(C2=O)N)SC1)C(=O)O

InChI

InChI=1S/C9H10N2O3S/c1-2-4-3-15-8-5(10)7(12)11(8)6(4)9(13)14/h2,5,8H,1,3,10H2,(H,13,14)/t5-,8-/m1/s1

InChIKey

GQLGFBRMCCVQLU-SVGQVSJJSA-N

LogP

-0.2465

Topological Polar Surface Area

83.63 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

391

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-AVCA
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid
GQLGFBRMCCVQLU-SVGQVSJJSA-N
AS-14226
DTXSID80428501
(6R-trans)-7-Amino-3-ethenyl-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
SCHEMBL5284761
AC-5550
NS00011507
AMY28675
79349-82-9
AKOS015892740
(6R,7R)-7-amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CS-0144678
7-Amino-3-vinyl-3-cephem-4-carboxylic acid
7beta-amino-3-vinyl-3-cephem-4-carboxylic acid
7-Amino-3-vinyl-3-cephem-4-carboxylic Acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-ethenyl-8-oxo-, (6R,7R)-
7-AMINO-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID (7-AVCA)
Cefixime Impurity 7 AVCA
(6R,7R)-7-Amino-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefdinir CP impurity C
(6R,7R)-7-amino-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

MDL Number

MFCD07782149

FAQ

What is 7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9)?

7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) is a cepham derivative with the chemical formula C11H14N2O5S. It features an amino group, a vinyl substituent, and a carboxylic acid group, making it a key intermediate in pharmaceutical synthesis. This compound is typically a white solid with moderate solubility in water and is valued for its structural versatility in drug development.

What are the main uses of 7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9)?

7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) is primarily used in the pharmaceutical industry as a precursor for cephalosporin antibiotics. Its unique chemical structure enables the synthesis of broad-spectrum antimicrobial agents. Additionally, it serves as a building block in organic chemistry for developing other bioactive compounds and pharmaceutical intermediates.

Is 7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) safe?

7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) is generally considered safe when handled properly, but it requires adherence to standard chemical safety protocols. Limited toxicity data suggests it is not highly hazardous, though protective measures like gloves, goggles, and well-ventilated areas are recommended. Always follow OSHA guidelines for safe handling and storage.

How should 7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) be stored?

7-Amino-3-vinyl-3-cephem-4-carboxylic Acid (CAS: 79349-82-9) should be stored in a cool, dry place (ideally 2-8°C), protected from light and moisture. Keep in a sealed, airtight container to maintain stability. Avoid exposure to heat or humidity to prevent degradation, and ensure storage conditions comply with chemical preservation standards for long-term use.