meta-Glimepiride Impurity. | CAS No. 791104-62-6

meta-Glimepiride Impurity.

Basic Information

CAS Number

791104-62-6

Molecular Formula

C24H34N4O5S

Molecular Weight

490.62 g/mol

AD

Basic Physical Properties

Density

1.29

CCC1=C(CN(C1=O)C(=O)NCCC2=CC(=CC=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C

InChI

InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-13-12-18-6-5-7-20(14-18)34(32,33)27-23(30)26-19-10-8-16(2)9-11-19/h5-7,14,16,19H,4,8-13,15H2,1-3H3,(H,25,31)(H2,26,27,30)

InChIKey

XBXROPCBZLGQMA-UHFFFAOYSA-N

LogP

3.0740000000000016

Topological Polar Surface Area

124.68 Ų

Hydrogen Bond Donor/Acceptor

3 / 9

Complexity

903

Synonyms & References

English

  • 1H-PYRROLE-1-CARBOXAMIDE, 3-ETHYL-2,5-DIHYDRO-4-METHYL-N-(2-(3-(((((TRANS-4-METHYLCYCLOHEXYL)AMINO)CARBONYL)AMINO)SULFONYL)PHENYL)ETHYL)-2-OXO-
  • Glimepiride Imp. D (EP); Glimepiride USP Related Compound D; Glimepiride USP RC D; 1-[[3-[2-[[(3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulphonyl]-3-(trans-4-methylcyclohexyl)urea; Glimepiride Related Compound D; Glimepiride Impurity D
  • Q27266352
  • SCHEMBL14965695
  • 3-Ethyl-4-methyl-N-(3-(N-((trans-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
  • 791104-62-6
  • UNII-757209Q8G8
  • SCHEMBL14965698
  • 757209Q8G8
  • FT-0668979
  • CS-0165192
  • meta-Glimepiride Impurity.
  • meta-Glimepiride Impurity
  • GLIMEPIRIDE 3-ISOMER
  • Glimepiride Impurity D
  • 4-ethyl-3-methyl-N-[2-[3-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
  • GLIMEPIRIDE IMPURITY D [EP IMPURITY]
  • 1-((3-(2-(((3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl)carbonyl)amino)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea
  • 1-[[3-[2-[[(3-Ethyl-4-methyl-2-oxo-2,3-dihydro-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulphonyl]-3-(trans-4-methylcyclohexyl)urea
  • 3-ethyl-4-methyl-N-(3-(N-(((1r,4r)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide? (Glimepiride Impurity pound(c)
  • Glimepiride 3-Isomer Discontinued. Please see G410160
  • GLIMEPIRIDE USP RC D (""META ISOMER"")
  • 3-Ethyl-2,5-dihydro-4-methyl-N-[2-[3-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
  • Glimepride 3-Isomer
  • 1-[[m-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea
  • 3-ethyl-4-methyl-N-(3-(N-(((1r,4r)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

MDL Number

MFCD21363628

FAQ

What regulatory guidelines apply to meta-Glimepiride Impurity (CAS: 791104-62-6)?

Meta-Glimepiride Impurity (CAS: 791104-62-6) is subject to regulatory guidelines such as GHS classification for hazard communication, REACH regulations for chemical registration, and FDA/EPA requirements for pharmaceutical and environmental safety. Manufacturers must comply with these regulations to ensure the safe handling, storage, and disposal of the impurity.

Are there alternatives to meta-Glimepiride Impurity (CAS: 791104-62-6) in synthesis?

In the synthesis of meta-Glimepiride, alternative reagents such as glimepiride or its precursors can be used as substitutes. These alternatives can help reduce the formation of impurities, including meta-Glimepiride Impurity (CAS: 791104-62-6), by optimizing reaction conditions and using more selective reagents.

What is the market or research trend for meta-Glimepiride Impurity (CAS: 791104-62-6)?

The market for meta-Glimepiride Impurity (CAS: 791104-62-6) is closely linked to the broader demand for glimepiride and its derivatives in the treatment of diabetes. Research is focusing on developing more efficient and selective synthesis methods to minimize the formation of this impurity. Additionally, there is an increasing emphasis on green chemistry and sustainable waste management, which influences the demand for more environmentally friendly production processes.

How should waste containing meta-Glimepiride Impurity (CAS: 791104-62-6) be handled?

Waste containing meta-Glimepiride Impurity (CAS: 791104-62-6) should be handled according to the regulations outlined in REACH, EPA, and local environmental laws. The waste should be collected in appropriate containers, labeled with the correct hazard information, and disposed of through professional waste disposal services. Environmental protection measures include proper sealing and storage to prevent leaks, and adherence to incineration or chemical treatment methods to ensure complete destruction of the impurity.

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