2-Chloro-5-methyl-4-pyridinamine

Basic Information

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CAS Number

79055-62-2

Molecular Formula

C6H7ClN2

Molecular Weight

142.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

115 ºC

Boiling Point

283.3℃ at 760 mmHg

Density

1.260±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CC1=CN=C(C=C1N)Cl

InChI

InChI=1S/C6H7ClN2/c1-4-3-9-6(7)2-5(4)8/h2-3H,1H3,(H2,8,9)

InChIKey

CJGKOPNIXJWHKF-UHFFFAOYSA-N

LogP

1.6256199999999998

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Synonyms & References

English

2-chloro-5-methylpyridin-4-amine
FT-0699438
4-Pyridinamine,2-chloro-5-methyl-
AM85914
4-PYRIDINAMINE, 2-CHLORO-5-METHYL-
4-AMINO-2-CHLORO-5-METHYLPYRIDINE
2-chloro-5-methyl-4-pyridinamine
2-Chloro-5-methyl-pyridin-4-ylamine
EN300-102234
AC-25001
A1-11378
J-515983
A839562
2-Chloro-5-methyl-pyridin-4-amine;4-Amino-2-chloro-5-methylpyridine
TS-01857
SCHEMBL2596935
AB65156
SY035222
AKOS006361159
CS-W021662
CJGKOPNIXJWHKF-UHFFFAOYSA-N
MFCD11977435
DTXSID70505451
79055-62-2
4-amino-5-methyl-2-chloropyridine
2-Chloro-5-methylpyridin-4-amine
2-Chloro-5-methyl-4-pyridinamine
4- Pyridinamine, 2-chloro-5-methyl-
2-chloranyl-5-methyl-pyridin-4-amine
4-amino-2-chloro-5-methylpyridine
4-Pyridinamine,2-chloro-5-methyl

MDL Number

MFCD11977435

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2)?

2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2) is a crystalline solid with a molecular weight of approximately 147.59 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. Chemically, it is known for its reactivity towards nucleophiles and its ability to form coordination complexes with certain metals. It is also slightly basic and can react with acids to form salts.

How is 2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2) typically synthesized?

2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2) is commonly synthesized via the condensation of 3-chloro-4-pyridinamine with methanol in the presence of a catalyst such as p-toluenesulfonic acid. The reaction is typically conducted under mild conditions and yields a pure product. The selectivity and yield of the reaction can be optimized by adjusting the reaction conditions and ensuring proper purification methods.

What industries use 2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2)?

2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2) is primarily used in the pharmaceutical industry for the synthesis of various pharmaceutical compounds. It is also relevant in the polymer industry for the development of special polymers. Additionally, it may find applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2)?

When handling 2-Chloro-5-methyl-4-pyridinamine (CAS: 79055-62-2), it is important to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be handled according to standard procedures, and the material safety data sheet (MSDS) should be consulted for specific spill and disposal instructions. Always follow safety guidelines and work with a trained professional.