2-Methylpropanoyl chloride

Basic Information

View in Editor

CAS Number

79-30-1

Molecular Formula

C4H7ClO

Molecular Weight

106.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

−90 °C

Boiling Point

93°C

Density

1.017 g/mL at 25 °C

Solubility

Miscible with chloroform, glacial acetic acid, ether, toluene, methylene chloride and benzene.

Refractive Index

n20/D 1.407(lit.)

Vapor Pressure

0.07 mmHg ( 20 °C)

SMILES

View in Editor

CC(C)C(=O)Cl

InChI

InChI=1S/C4H7ClO/c1-3(2)4(5)6/h3H,1-2H3

InChIKey

DGMOBVGABMBZSB-UHFFFAOYSA-N

LogP

1.4078

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

58.6

Safety Information

View Safety Information

GHS Hazard Pictograms

H225

H314

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 3 Class 3

Sensitiveness

Moisture Sensitive

Explosive Limit

2.1-8.2%(V)

Synonyms & References

English

2-Methylpropanoyl chloride
isobutyrl chloride
ISOBUTYROYL CHLORIDE (IBCL)
Isobutyryl chloride

MDL Number

MFCD00000717

Customs Code

29159080

FAQ

What are the physical and chemical properties of 2-Methylpropanoyl chloride (CAS: 79-30-1)?

2-Methylpropanoyl chloride is a colorless or slightly yellow liquid with a molecular weight of 100.07 g/mol. It is slightly soluble in water and highly soluble in organic solvents. The compound is highly reactive, particularly with nucleophiles and bases, and can readily undergo hydrolysis to form 2-methylpropionic acid.

How is 2-Methylpropanoyl chloride (CAS: 79-30-1) typically synthesized?

2-Methylpropanoyl chloride is typically synthesized by the chlorination of 2-methylpropanoyl alcohol. The reaction is usually carried out in the presence of a Lewis acid catalyst such as aluminum chloride to promote electrophilic substitution at the alcohol moiety.

What industries use 2-Methylpropanoyl chloride (CAS: 79-30-1)?

2-Methylpropanoyl chloride finds application in the pharmaceutical industry for the synthesis of various intermediates and drugs, as well as in the polymer industry for the synthesis of certain polyesters and polymers. It is also used in the production of sensors and semiconductors.

What precautions should be taken when handling 2-Methylpropanoyl chloride (CAS: 79-30-1)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 2-methylpropanoyl chloride. The substance should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and disposed of according to safety data sheet (SDS) guidelines.