Calcitriol-d | CAS No. 78782-99-7

Calcitriol-d

Basic Information

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CAS Number

78782-99-7

Molecular Formula

C27H38D6O3

Molecular Weight

422.68 g/mol

Chemical Classification

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

77-79°C

Flash Point

14℃

SMILES

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CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C

InChI

InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/t18-,22-,23-,24+,25+,27-/m1/s1/i3D3,4D3

InChIKey

GMRQFYUYWCNGIN-OWKVYBDPSA-N

LogP

5.704700000000007

Topological Polar Surface Area

60.69 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

688

Safety Information

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Stability

Light and temperature sensitive

Synonyms & References

English

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E)-(26,26,26,27,27,27-~2~H_6_)-9,10-Secocholesta-5,7,10-triene-1,3,25-triol
AC-26352
HY-76814
MFCD15071365
MS-27425
CS-0809
78782-99-7
DTXSID90515335
Calcitriol-26,26,26,27,27,27-d6
Calcitriol D6
AKOS025401844
Calcitriol-d6
Silkis-d6
Calcijex-d6
Toptriol-d6
Topitriol-d6
Rocaltrol-d6
Ro 21-5535-d6
1a,25-Dihydroxyvitamin D3-d6
1a,25-Dihydroxycholecalciferol-d6
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-di
Panbonis-d6
Soltriol-d6
1alpha,25-Dihydroxyvitamin D3-[26,26,26,27,27,27]-d6
(1R,3S,5Z)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1-methyl-5-(methyl-d3)hexyl-6,6,6-d3]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
Calcitriol-d
(1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-(methyl-d3)heptan-2-yl-7,7,7-d3)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol

MDL Number

MFCD31814246

FAQ

What is Calcitriol-d (CAS: 78782-99-7)?

Calcitriol-d (CAS: 78782-99-7) is a form of vitamin D3 that is metabolically activated to its most potent form, 1,25-dihydroxyvitamin D3. It is a lipid-soluble hormone involved in calcium and phosphate metabolism, crucial for bone health and mineralization.

What are the main uses of Calcitriol-d (CAS: 78782-99-7)?

Calcitriol-d (CAS: 78782-99-7) is primarily used in the treatment of hypocalcaemia, osteoporosis, and renal osteodystrophy. It is also prescribed for vitamin D deficiency and to manage secondary hyperparathyroidism in chronic kidney disease patients.

Is Calcitriol-d (CAS: 78782-99-7) safe?

Calcitriol-d (CAS: 78782-99-7) is generally considered safe when used under medical supervision. However, excessive doses can lead to hypercalcemia and hypercalciuria, necessitating close monitoring and adherence to prescribed dosage.

How should Calcitriol-d (CAS: 78782-99-7) be stored?

Calcitriol-d (CAS: 78782-99-7) should be stored in a cool, dry place, away from direct sunlight and heat sources. It is recommended to keep the medication in its original packaging to protect it from moisture and light. Store at a temperature not exceeding 25°C (77°F) and ensure the container is tightly closed to maintain potency.