Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | CAS No. 78756-33-9
Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
Basic Information
CAS Number
78756-33-9
Molecular Formula
C15H14ClN3O3
Molecular Weight
319.75 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- SCHEMBL5748925
- BDBM50034839
- 8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid ethyl ester(Ro 15-1310)
- ETHYL 8-CHLORO-5-METHYL-6-OXO-5,6-DIHYDRO-4H-BENZO(F)IMIDAZO(1,5-A)(1,4)DIAZEPINE-3-CARBOXYLATE
- FLUMAZENIL IMPURITY F [EP IMPURITY]
- RO 15-1310
- Z3247580758
- Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
- AKOS030600134
- Ro-151310
- Ro-15-1310
- UNII-ZRD5QFZ6DV
- Ethyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate
- ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- CHLOROFLUMAZENIL [USP IMPURITY]
- 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacidethylester
- ethyl 8-chloro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- QORLMYYHZLDYOR-UHFFFAOYSA-N
- 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester
- 78756-33-9
- ZRD5QFZ6DV
- DTXSID40229273
- CHEMBL415290
- CHLOROFLUMAZENIL
- 8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid ethyl ester
- 4H-Imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylic acid, 8-chloro-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
- Flumazenil Impurity F
- 4H-Imidazo[1,5-a][1,4] benzodiazepine-3-carboxylic acid, 8-chloro-5,6-dihydro-5- methyl-6-oxo-, ethyl ester
- 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester
- ethyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
- Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]b enzodiazepine-3-carboxylate
FAQ
What are the physical and chemical properties of Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (CAS: 78756-33-9)?
Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate is a crystalline white solid with a molecular weight of approximately 324.02 g/mol. It has a low solubility in water (less than 0.1g/100mL at 25°C) and is soluble in organic solvents like methanol, ethanol, and dichloromethane. The compound is highly reactive, particularly towards nucleophiles and reducing agents.
How is Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (CAS: 78756-33-9) typically synthesized?
Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate can be synthesized via a multi-step process. Initially, a 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-3-one intermediate is prepared. This is then reacted with 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid using an esterification procedure, typically catalyzed by a strong acid like sulfuric acid or phosphoric acid, to obtain the final product with a high yield of 80-90%.
What industries use Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (CAS: 78756-33-9)?
Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate is primarily used in the pharmaceutical industry for its potential applications as an intermediate in drug synthesis. It is also utilized in the development of certain sensors and as a building block in organic synthesis for the production of various chemical compounds.
What precautions should be taken when handling Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate (CAS: 78756-33-9)?
Precautions when handling Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate include wearing appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. The compound should be stored in a cool, dry place away from sources of heat and moisture. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always refer to the material safety data sheet (MSDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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