4-Bromo-2,6-diphenylpyridine

Basic Information

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CAS Number

78500-89-7

Molecular Formula

C17H12BrN

Molecular Weight

310.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

90 ºC (ethanol )

Density

1.352±0.06 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (9.9E-3 g/L) (25 ºC),

SMILES

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C1=CC=C(C=C1)C2=CC(=CC(=N2)C3=CC=CC=C3)Br

InChI

InChI=1S/C17H12BrN/c18-15-11-16(13-7-3-1-4-8-13)19-17(12-15)14-9-5-2-6-10-14/h1-12H

InChIKey

AVESHYKDJMFQGJ-UHFFFAOYSA-N

LogP

5.178100000000003

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

242

Synonyms & References

English

A851625
FT-0744794
78500-89-7
4-Bromo-2,6-diphenylpyridine
DTXSID80508150
2,6-diphenyl-4-broMo-pyridine
SCHEMBL14951425
2,6-diphenyl-4-bromo-pyridine
Pyridine, 4-bromo-2,6-diphenyl-

MDL Number

MFCD26743610

FAQ

What are the physical and chemical properties of 4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7)?

4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7) is a crystalline solid with a molecular weight of approximately 346.24 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and dichloromethane. Chemically, it exhibits moderate reactivity towards nucleophiles, particularly under basic conditions. It is stable under neutral and acidic conditions but should be handled with care in the presence of strong oxidizing agents.

How is 4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7) typically synthesized?

4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7) can be synthesized via a pyridine substitution reaction. A common method involves the reaction of 2,6-diphenylpyridine with bromine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction provides a high yield of the target product with good selectivity.

What industries use 4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7)?

4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7) finds applications in pharmaceuticals, where it acts as an intermediate in the synthesis of various drug candidates. It is also used in the development of sensors and semiconductors due to its unique electronic properties. Additionally, it is employed in the production of certain polymer materials.

What precautions should be taken when handling 4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7)?

When handling 4-Bromo-2,6-diphenylpyridine (CAS: 78500-89-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be performed in a well-ventilated area or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.