1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea

Basic Information

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CAS Number

78491-02-8

Molecular Formula

C8H14N4O7

Molecular Weight

278.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

No data available

Boiling Point

421.04°C (rough estimate)

Density

1.4734 (rough estimate)

Flash Point

No data available

Refractive Index

1.6590 (estimate)

SMILES

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OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

InChI

InChI=1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

InChIKey

SOROIESOUPGGFO-UHFFFAOYSA-N

LogP

-3.6124999999999985

Topological Polar Surface Area

153.88 Å²

Hydrogen Bond Donor/Acceptor

5 / 11

Complexity

376

Safety Information

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Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

H341 Suspected of causing genetic defects
Germ cell mutagenicity

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

易吸潮

Toxicity

LD50 orally in rats: 2.57 g/kg; dermally in rabbits: >2.0 g/kg (Berke, Rosen)

Synonyms & References

English

1-(1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)-1,3-bis(hydroxymethyl)urea
DIAZOLIDINYL UREA
N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxymethyl)-urea
germall11
imidazolidinylurea11
n-(1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-n,n’-bis(hydroxymethyl
n-(hydroxymethyl)-n-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-n’-(hyd
N-(Hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N’-(hydroxymethyl)urea
urea,n-(1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-n,n’-bis(hydroxymet
urea,n-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-n,n’-bis(hydroxymet
Urea,N-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N’-bis(hydroxymethyl)-
1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
MicrocideIvtm
Germall
N-(HYDROXYMETHYL)-N-(1,3-DIHYDROXYMETHYL-2,5-DIOXO-4-IMIDA.
DIAZOLIDINYLUREA (GERMALL II)
1,3-Bis(hydroxymethyl)-5-[1,3-bis(hydroxymethyl)ureido]hydantoin
Germall Ⅱ
Diazo alkylurea (diazo imidazole alkylurea)
1-[1,3-bis(hydroxymethyl)-2,5-dioxo-imidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
Diazolidinylurea
Germall II
Germall 11
Imidazolidinyl urea 11
N,N'-Bis(hydroxymethyl) urea
n-[1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-n,n'-bis(hydroxymethyl)urea
Diazolidinyl urea, 95%
DSSTox_CID_9559
N-(Hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N'-(hydroxymethyl) urea
Urea,
Silicon dioxide

MDL Number

MFCD03547942

Customs Code

2933990090

FAQ

What is 1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea (CAS: 78491-02-8)?

1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea, with CAS number 78491-02-8, is a multifunctional organic compound containing urea and imidazolidine groups. It is known for its potential applications in pharmaceutical and chemical research due to its structural versatility and reactivity.

What are the main uses of 1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea (CAS: 78491-02-8)?

This compound is primarily used in pharmaceutical research as a building block for drug development, particularly in the synthesis of antiviral and antifungal agents. It also finds application in chemical synthesis and as a stabilizer in certain formulations.

Is 1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea (CAS: 78491-02-8) safe?

As a chemical compound, 1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea is generally considered safe when handled properly. However, it should be treated with care, and appropriate safety measures such as gloves and ventilation are recommended to minimize exposure risks.

How should 1-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-1,3-bis(hydroxymethyl)urea (CAS: 78491-02-8) be stored?

To maintain stability and prevent degradation, this compound should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It should be kept in a sealed container to avoid moisture and air exposure, and stored away from incompatible substances.