{2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl}methanol

Basic Information

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CAS Number

78441-69-7

Molecular Formula

C7H12N2OS

Molecular Weight

172.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

273.1°C at 760 mmHg

Density

1.208

Flash Point

119°C

Refractive Index

1.574

SMILES

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CN(C)CC1=NC(=CS1)CO

InChI

InChI=1S/C7H12N2OS/c1-9(2)3-7-8-6(4-10)5-11-7/h5,10H,3-4H2,1-2H3

InChIKey

BIEFSXASVIQOOS-UHFFFAOYSA-N

LogP

0.6969999999999998

Topological Polar Surface Area

36.36 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

121

Synonyms & References

English

2-(Dimethylaminomethyl)-4-Thiazole Methanol
[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methanol
DTXSID30365356
EN300-36208
(2-Dimethylaminomethyl-thiazol-4-yl)-methanol
4-Thiazolemethanol, 2-[(dimethylamino)methyl]-
78441-69-7
2-Dimethylaminomethyl-4-thiazolemethanol
AKOS000302713
6K6QKG6ALN
SCHEMBL4339516
CS-0119845
2-(Dimethylaminomethyl) -4-thiazolemethanol
A839422
(2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol
2-(dimethylaminomethyl)-4-thiazolemethanol, AldrichCPR
FT-0641677
Nizatidine impurity J [EP]
2-((Dimethylamino)methyl)-4-thiazolemethanol
InChI=1/C7H12N2OS/c1-9(2)3-7-8-6(4-10)5-11-7/h5,10H,3-4H2,1-2H
2-Dimethylaminomethyl-4-hydroxvmethylthiazole
Z362770690
VS-12214
2-[(Dimethylamino)methyl]-4-thiazolemethanol
{2-[(dimethylamino)methyl]-1,3-thiazol-4-yl}methanol
4-Thiazolemethanol, 2-((dimethylamino)methyl)-
UNII-6K6QKG6ALN
2-Dimethylaminomethyl-4-hydroxymethylthiazole
(2-((dimethylamino)methyl)thiazol-4-yl)methanol
MFCD06407647
AC-20415

MDL Number

MFCD06407647

Customs Code

2934100090

FAQ

What are the physical and chemical properties of (2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7)?

(2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7) is a white crystalline solid with a molecular weight of approximately 220.24 g/mol. It has a high solubility in organic solvents such as ethanol and methanol, but is poorly soluble in water. This compound is relatively stable under normal conditions but can react with strong acids or bases. It is often used in chemical synthesis due to its reactivity and unique functional groups.

How is (2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7) typically synthesized?

(2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7) can be synthesized via the reaction of 1,3-thiazol-4-amine with methyl iodide and dimethylamine. The process involves the use of a base such as sodium hydride to provide the necessary nucleophilicity, resulting in a high yield of the desired product. This synthesis is commonly carried out in an inert atmosphere to prevent side reactions.

What industries use (2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7)?

(2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7) is used in various industries, particularly in pharmaceuticals where it serves as a precursor for drug synthesis. It is also utilized in the production of polymers and as a sensor material due to its unique chemical properties. Additionally, it finds application in the semiconductor industry for certain purification processes.

What precautions should be taken when handling (2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7)?

When handling (2-[(Dimethylamino)methyl]-1,3-thiazol-4-yl)methanol (CAS: 78441-69-7), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled with caution, using appropriate absorbent materials and following standard laboratory procedures. Always consult the safety data sheet (SDS) for detailed handling and disposal information.