(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Basic Information

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CAS Number

78287-27-1

Molecular Formula

C22H20N2O4

Molecular Weight

376.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Cryst.

Melting Point

271-274°C

Density

1.43

Solubility

Chloroform and Methanol Mixture; DMSO

Specific Rotation

+40 - +46° (c=0.4, CHCl3:MeOH=8:2)

SMILES

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CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=CC=CC=C12

InChI

InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1

InChIKey

MYQKIWCVEPUPIL-QFIPXVFZSA-N

LogP

2.6420000000000003

Topological Polar Surface Area

81.42 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

787

Safety Information

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Hazard Statement

Hazard Class

Class 6.1 Class 6.1

Storage Conditions

2-8℃

Synonyms & References

English

(S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
7-Ethylcamptothecin
T00038
(4s)-4,11-diethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione
20(S)-7-ethylcamptothecin
7-ethyl-20(S)-camptothecin
SN 22
(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
7-ethyl-camptothecin
7-Ethylcamptothecin, AldrichCPR
MYQKIWCVEPUPIL-QFIPXVFZSA-N
7-Ethylcamptotrecin,7-Ethyl-20(S)-camptothecin,SN 22
(S)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione

MDL Number

MFCD06657922

Customs Code

2942000000

FAQ

What is (4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (CAS: 78287-27-1)?

This compound is a complex organic molecule belonging to the quinoline class, characterized by a fused ring system with hydroxy and diethyl substituents. Its chemical formula is C21H22N2O4, and it exhibits structural features typical of bioactive heterocyclic compounds, often studied for potential pharmaceutical applications.

What are the main uses of (4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (CAS: 78287-27-1)?

This compound is primarily used in pharmaceutical research as a potential lead molecule for drug development. Its unique structure may contribute to biological activities, such as enzyme inhibition or receptor modulation, making it relevant in studies related to medicinal chemistry and therapeutic applications.

Is (4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (CAS: 78287-27-1) safe?

Safety data for this compound is limited, but as a complex organic chemical, it should be handled with care. Precautions include wearing protective gloves and eyewear, avoiding inhalation, and following standard laboratory safety protocols. Its toxicity profile requires evaluation under controlled conditions to ensure compliance with safety regulations.

How should (4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione (CAS: 78287-27-1) be stored?

Store this compound in a sealed, airtight container at room temperature (15-25°C) in a cool, dry location away from light. Maintain low humidity to preserve stability, and ensure it is kept in a well-ventilated area to prevent exposure to air or moisture. Refrigeration may be necessary for long-term storage depending on specific conditions.