2-(2-Amino-3-benzoylphenyl)acetamide

Basic Information

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CAS Number

78281-72-8

Molecular Formula

C15H14N2O2

Molecular Weight

254.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

No data avaiable

Melting Point

182.0 to 186.0 deg-C

Boiling Point

562.5°C at 760 mmHg

Density

1.3±0.1 g/cm3

Flash Point

294.0±30.1 °C

Solubility

DMSO: ≥5mg/mL

Refractive Index

1.641

Vapor Pressure

0.0±1.5 mmHg at 25°C

SMILES

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C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N

InChI

InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)

InChIKey

QEFAQIPZVLVERP-UHFFFAOYSA-N

LogP

1.5276

Topological Polar Surface Area

86.18 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

337

Safety Information

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GHS Hazard Pictograms

H400

Hazard Statement

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Hazard Class

Class 9 Class 9

Synonyms & References

English

Benzeneacetamide, 2-amino-3-benzoyl-
QEFAQIPZVLVERP-UHFFFAOYSA-N
2-(2-Amino-3-benzoylphenyl)acetamide
NEPAFENAC (USP-RS)
NEPAFENAC [EMA EPAR]
NEPAFENAC (MART.)
NEPAFENAC [USP-RS]
SCHEMBL93835
AB01274763_02
SMR002529588
AC-6949
Nevanac (TN)
HY-17357
Nevanac
HMS3884E07
MFCD08067732
SW219197-1
CHEBI:75922
CAS-78281-72-8
DB06802
78281-72-8
MLS003915618
2-amino-3-benzoyl-benzeneacetamide
J-507774
BDBM50228731
Nepafenac [USAN:INN:BAN:JAN]
2-(2-amino-3-benzoyl-phenyl)acetamide
FT-0603701
Nepafenac (JAN/USAN/INN)
NCGC00185741-01
Nepafenac, >=98% (HPLC)

MDL Number

MFCD08067732

Customs Code

2924299090

FAQ

What is 2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8)?

2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) is an organic compound belonging to the acetamide class. Its chemical formula is C15H14N2O2, and it is characterized by a benzoyl group attached to a phenyl ring with an amino functional group. The compound is typically a white solid with moderate solubility in polar solvents, commonly used as an intermediate in pharmaceutical synthesis.

What are the main uses of 2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8)?

2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) is primarily used in pharmaceutical research and development as a building block for drug molecules. It serves as an intermediate in the synthesis of antiviral and anti-inflammatory agents. Additionally, it is employed in chemical research for creating derivatives with tailored biological activities.

Is 2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) safe?

2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) is considered safe when handled properly. It has a low toxicity profile but may cause mild irritation upon contact with skin or eyes. Safety precautions include wearing gloves, goggles, and a lab coat, and working in a well-ventilated area. Always follow standard chemical safety guidelines and regulatory requirements for handling.

How should 2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) be stored?

2-(2-Amino-3-benzoylphenyl)acetamide (CAS: 78281-72-8) should be stored in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a sealed container to prevent moisture absorption, and avoid exposure to heat or direct light. Ensure storage in a well-ventilated area to maintain stability and safety.