5-(Ethoxymethyl)-2-pyridinamine | CAS No. 782431-91-8

5-(Ethoxymethyl)-2-pyridinamine

Basic Information

CAS Number

782431-91-8

Molecular Formula

C8H12N2O

Molecular Weight

152.2 g/mol

AD

Basic Physical Properties

CCOCC1=CN=C(C=C1)N

InChI

InChI=1S/C8H12N2O/c1-2-11-6-7-3-4-8(9)10-5-7/h3-5H,2,6H2,1H3,(H2,9,10)

InChIKey

NAYXZUAKLJFPDW-UHFFFAOYSA-N

LogP

1.2003

Topological Polar Surface Area

48.14 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

108

Synonyms & References

English

  • 782431-91-8
  • 5-(Ethoxymethyl)pyridin-2-amine
  • SCHEMBL14535423
  • CS-0455670
  • MFCD16689762
  • SB54386
  • A901069
  • J-516344
  • AKOS011476809
  • DTXSID80666901
  • 2-Pyridinamine,5-(ethoxymethyl)-(9CI)
  • 2-Pyridinamine,5-(ethoxymethyl)-

MDL Number

MFCD16689762

FAQ

What are the physical and chemical properties of 5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8)?

5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8) is a solid with a crystalline form. Its molecular weight is approximately 185.2 g/mol. The compound has a moderate solubility in common organic solvents but is poorly soluble in water. It shows moderate reactivity towards nucleophiles and is stable under normal storage conditions.

How is 5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8) typically synthesized?

5-(Ethoxymethyl)-2-pyridinamine is typically synthesized via the condensation of 2-pyridinemethanol with ethyl acetate in the presence of a base such as sodium hydride. The reaction yields the title compound with good selectivity and moderate to high yield depending on the conditions.

What industries use 5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8)?

5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8) is used in the pharmaceutical and chemical industries. It serves as a precursor in the development of various pharmaceutical compounds and as a building block in organic synthesis. Its applications include the synthesis of heterocyclic compounds and drug intermediates.

What precautions should be taken when handling 5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8)?

When handling 5-(Ethoxymethyl)-2-pyridinamine (CAS: 782431-91-8), it is important to use appropriate personal protective equipment (PPE), including gloves and goggles. Ensure that the reaction is carried out under a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.

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