Aztreonam | CAS No. 78110-38-0

Aztreonam

Basic Information

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CAS Number

78110-38-0

Molecular Formula

C13H17N5O8S2

Molecular Weight

435.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

220°C (dec.)

Boiling Point

No data available

Density

1.83

Water Solubility

Soluble in DMF/water (1:1) at 50 mg/ml

Flash Point

No data available

Refractive Index

1.6460 (estimate)

Vapor Pressure

No data available

Specific Rotation

-26° - -32° (c=0.5, H2O)

SMILES

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CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N

InChI

InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

InChIKey

WZPBZJONDBGPKJ-VEHQQRBSSA-N

LogP

-1.1724999999999979

Topological Polar Surface Area

201.57999999999998 Å²

Hydrogen Bond Donor/Acceptor

5 / 13

Complexity

808

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BRN 3577211
SR-01000841814-3
BCP9000372
PROPANOIC ACID, 2-(((1-(2-AMINO-4-THIAZOLYL)-2-((2-METHYL-4-OXO-1-SULFO-3-AZETIDINYL)AMINO)-2-OXOETHYLIDENE)AMINO)OXY)-2-METHYL-, (2S-(2.ALPHA.,3.BETA.(Z)))-
78110-38-0
Aztreonamum
BRD-K62607865-001-03-0
SQ26776
HMS2095F11
aztreonam
Cayston
AZTREONAM [USAN]
Aztreonamum (Latin)
CHEMBL158
AZTREONAM (MART.)
HMS3712F11
Aztreonam E-Isomer
149496-40-2
AS-13760
Azthreonam
2-((((1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- (((2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino) -2- oxoethylidene)amino)oxy)-2-methylpropanoic acid
Aztreon
MFCD00072145
Aztreonam, United States Pharmacopeia (USP) Reference Standard
rel-Aztreonam
2-((Z)-(2-Aminothiazol-4-yl)-((2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-ylcarbamoyl)methyleneaminooxy)-2-methyl-1-propanoic acid
BSPBio_000109
AZTREONAM [VANDF]
AZTREONAM (USP MONOGRAPH)
SMR004703537
Az threonam

MDL Number

MFCD00072145

Customs Code

2942000000

FAQ

What is Aztreonam (CAS: 78110-38-0)?

Aztreonam is an antibiotic medication used primarily to treat bacterial infections. It belongs to the monobactam class of beta-lactam antibiotics and has the chemical formula C12H17N3O4S. It is a white to off-white powder that is soluble in water and has a broad spectrum of activity against Gram-negative bacteria. Aztreonam is commonly used in clinical settings for respiratory tract infections and other bacterial conditions.

What are the main uses of Aztreonam (CAS: 78110-38-0)?

Aztreonam is mainly used in pharmaceuticals as an antibiotic to treat infections caused by Gram-negative bacteria. It is effective against organisms such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli. Additionally, it is used in research for studying bacterial resistance and in industrial settings for the production of antibiotics and other chemical compounds.

Is Aztreonam (CAS: 78110-38-0) safe?

Aztreonam is considered safe when used as directed, but it should be handled with care to avoid skin irritation or allergic reactions. It is generally well-tolerated, with minimal risk of serious side effects. Safety standards for Aztreonam are established by regulatory bodies such as the FDA and WHO. Proper protective measures, including gloves and ventilation, are recommended during handling and storage.

How should Aztreonam (CAS: 78110-38-0) be stored?

Aztreonam should be stored in a cool, dry place away from direct light. It is stable at room temperature (around 20-25°C) and should be kept in a sealed, airtight container to prevent moisture ingress. Avoid exposure to high humidity or extreme temperatures to maintain its potency and effectiveness. Always follow the manufacturer's guidelines for storage conditions.