1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1) | CAS No. 7791-71-1

1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1)

Basic Information

CAS Number

7791-71-1

Molecular Formula

C35H34N2O5

Molecular Weight

484.55 g/mol

AD

Basic Physical Properties

CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)O

InChI

InChI=1S/C29H28N2O5.C6H6/c1-20-18-31(28(34)30-27(20)33)26-17-24(32)25(36-26)19-35-29(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23;1-2-4-6-5-3-1/h2-16,18,24-26,32H,17,19H2,1H3,(H,30,33,34);1-6H/t24-,25?,26+;/m0./s1

InChIKey

UYUKMLBIHCJKDF-VONYWGTISA-N

LogP

3.5021200000000032

Topological Polar Surface Area

93.55000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

765

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • MFCD00038462
  • 7791-71-1
  • 1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[(2R,4S,5R)-4-hydroxy-5-[(triphenylmethoxy)methyl]oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 5'-O-Tritylthymidine
  • 1-((2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
  • C29H28N2O5
  • CHEMBL2403290
  • 1-((2R,4S,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
  • PD128924
  • 5'-O-(Triphenylmetyl)thymidine
  • DS-2683
  • CS-W009623
  • NS00022370
  • AKOS016008529
  • J-700361
  • 1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
  • A839292
  • FZDHVUVGQXVYOP-JIMJEQGWSA-N
  • SCHEMBL1727537
  • 1-((2R,4S,5R)-4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
  • 5′-O-Tritylthymidine
  • 5'-O-TRITYLTHYMIDINE(5-OTT)
  • 5-Methyl-5'-O-trityl-2'-deoxyuridine
  • 5'-O-Tr-dThd
  • 5'-O-Triphenylmethylthymidine
  • 5'-O-tritythymidine
  • Trt-dT
  • 1-[(2R,4S,5S)-4-Hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

MDL Number

MFCD00038462

FAQ

What regulatory guidelines apply to 1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1) (CAS: 7791-71-1)?

The compound is subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous substances, including分类存储和运输要求。此外,根据欧盟REACH法规,该化合物可能需要进行注册和评估。美国FDA和EPA对涉及此类化合物的药物和化学品有特定的使用和报告要求。

Are there alternatives to 1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1) (CAS: 7791-71-1) in synthesis?

Alternative reagents for synthesis include similar 2,4-pyrimidinediones and other deoxy nucleoside derivatives. Isomers such as 2-deoxy-5-O-tert-butyldimethylsilyl-beta-D-glycero-pentofuranosyl-5-methyl-2,4(1H,3H)-pyrimidinedione are also used in related applications.

What is the market or research trend for 1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1) (CAS: 7791-71-1)?

Market trends show increasing interest in this compound for its use in antiviral drugs and nucleoside analogs. Research is focusing on its potential in antiretroviral therapy and as a starting material for customized nucleosides. Price trends suggest steady demand with small fluctuations based on manufacturing and raw material costs.

How should waste containing 1-[(4xi)-2-Deoxy-5-O-trityl-beta-D-glycero-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione - benzene (1:1) (CAS: 7791-71-1) be handled?

Waste containing this compound should be collected in proper containers and disposed of through incineration or professional waste disposal services. Follow local and national regulations for hazardous waste management, ensuring environmental protection measures are in place to prevent contamination. Proper labeling and documentation are required for waste disposal.

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