1-Piperazinecarbaldehyde

Basic Information

View in Editor

CAS Number

7755-92-2

Molecular Formula

C5H10N2O

Molecular Weight

114.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

88-91

Boiling Point

264-266 °C

Density

1.107 g/mL at 25 °C

Refractive Index

n20/D 1.512

SMILES

View in Editor

C1CN(CCN1)C=O

InChI

InChI=1S/C5H10N2O/c8-5-7-3-1-6-2-4-7/h5-6H,1-4H2

InChIKey

MSSDTZLYNMFTKN-UHFFFAOYSA-N

LogP

-0.9519999999999997

Topological Polar Surface Area

32.34 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

78.5

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

1-formyl piperazine
1-Formylpiperazine, technical, >=90% (GC)
N-formyl piperazine
piperazine-1-carbaldehyde;1-Piperazinecarboxaldehyde
F0194
F2190-0515
SCHEMBL8467
4-formyl-piperazine
FT-0636589
NSC-511082
7755-92-2
4-formylpiperazine
Piperazine-1-carboxaldehyde
Piperazine-1-carbaldehyde
1-Piperazinecarbaldehyde
1-Formylpiperazine, technical grade, 85%
EINECS 231-813-0
l-formylpiperazine
Q27452019
1-Formylpiperazine
MFCD00005963
1-Piperazinecarboxaldehyde
AS-15753
CS-W016606
A9816
EN300-20598
1-Formyl-piperazine
1-Formylpiperazine (>85%)
NS00037928
J-504634
piperazin-1-yl-methanone

MDL Number

MFCD00005963

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-Piperazinecarbaldehyde (CAS: 7755-92-2)?

1-Piperazinecarbaldehyde (CAS: 7755-92-2) is a colorless to light yellow crystalline solid with a molecular weight of 166.22 g/mol. It is slightly soluble in water but soluble in organic solvents. The compound is reactive and can undergo nucleophilic substitution reactions. It is also susceptible to hydrolysis under basic conditions.

How is 1-Piperazinecarbaldehyde (CAS: 7755-92-2) typically synthesized?

1-Piperazinecarbaldehyde (CAS: 7755-92-2) is typically synthesized by the condensation of piperazine with formaldehyde in the presence of an acid catalyst. Commonly, hydrochloric acid is used as the catalyst. The reaction yields a mixture of 1-piperazinecarbaldehyde and 2-piperazinecarbaldehyde, with 1-piperazinecarbaldehyde being the major product.

What industries use 1-Piperazinecarbaldehyde (CAS: 7755-92-2)?

1-Piperazinecarbaldehyde (CAS: 7755-92-2) finds applications in pharmaceuticals, where it serves as a precursor for some drugs. It is also used in the synthesis of certain polymers and as a functional group in sensor development. Additionally, it plays a role in the preparation of semiconducting materials.

What precautions should be taken when handling 1-Piperazinecarbaldehyde (CAS: 7755-92-2)?

When handling 1-Piperazinecarbaldehyde (CAS: 7755-92-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation exposure. Spills should be cleaned up using appropriate absorbent materials and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.