(2R)-2-Azetidinecarboxylic acid

Basic Information

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CAS Number

7729-30-8

Molecular Formula

C4H7NO2

Molecular Weight

101.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

209-211°C

Boiling Point

242°C at 760 mmHg

SMILES

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C1CNC1C(=O)O

InChI

InChI=1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m1/s1

InChIKey

IADUEWIQBXOCDZ-GSVOUGTGSA-N

LogP

-0.5671000000000002

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

91.7

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Temperature Sensitive - Do Not Heat Above 55°C

Synonyms & References

English

MFCD00800731
(R)-(+) AZETIDINE-2-CARBOXYLIC ACID
CHEMBL1599178
HY-W017755
2-Azetidinecarboxylic acid, (R)-
d-azetidine-2-carboxylic acid, AldrichCPR
D-Azetidine-2-carboxylic acid
(2R)-azetidine-2-carboxylic acid
(R)-azetidine-2-carboxylic acid
A9783
CS-W018478
Q27117375
2-Azetidinecarboxylic acid, D-
AM20100766
starbld0022633
SCHEMBL1527305
NCGC00015032-01
2-AZETIDINECARBOXYLIC ACID, (2R)-
UNII-J6H985U0M8
(2R)-azetidin-1-ium-2-carboxylate
CHEBI:38109
Lopac-A-0760
IADUEWIQBXOCDZ-GSVOUGTGSA-N
AKOS015854037
(R)-(+)-Azetidine-2-carboxylic acid
(R)-() Azetidine-2-carboxylic acid
(+)-AZETIDINECARBOXYLIC ACID
DS-10662
J6H985U0M8
7729-30-8
(R)-(-)-Azetidine-2-carboxylic acid

MDL Number

MFCD00800731

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (2R)-2-Azetidinecarboxylic acid (CAS: 7729-30-8)?

(2R)-2-Azetidinecarboxylic acid has a crystalline form and a molecular weight of approximately 140.14 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly in esterification and amidation reactions. It is used in the synthesis of pharmaceuticals and other organic compounds.

How is (2R)-2-Azetidinecarboxylic acid (CAS: 7729-30-8) typically synthesized?

(2R)-2-Azetidinecarboxylic acid can be synthesized via the Strecker synthesis, where aminoacetic acid is treated with formaldehyde and ammonia in the presence of a catalytic amount of a heavy metal salt such as mercuric chloride. Other methods include hydrogenation of azetidinone or through the Wittig reaction. The yield and selectivity depend on the chosen method and conditions.

What industries use (2R)-2-Azetidinecarboxylic acid (CAS: 7729-30-8)?

(2R)-2-Azetidinecarboxylic acid is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various drugs and is also utilized in the production of polymers, sensors, and semiconductors due to its unique chemical structure.

What precautions should be taken when handling (2R)-2-Azetidinecarboxylic acid (CAS: 7729-30-8)?

When handling (2R)-2-Azetidinecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Handle in a fume hood to minimize inhalation risk. Ensure proper ventilation and avoid contact with skin and eyes. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.