N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide

Basic Information

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CAS Number

77191-36-7

Molecular Formula

C14H18N2O2

Molecular Weight

246.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

149.0 to 153.0 deg-C

Boiling Point

458.5°C at 760 mmHg

Density

1.187

Flash Point

231.1 °C

Solubility

DMSO: >5mg/mL

Refractive Index

1.593

SMILES

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CC1=C(C(=CC=C1)C)NC(=O)CN2CCCC2=O

InChI

InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17)

InChIKey

NGHTXZCKLWZPGK-UHFFFAOYSA-N

LogP

1.8643399999999999

Topological Polar Surface Area

49.410000000000004 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

320

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Toxicity

LD50 in mice (mg/kg): 421 i.v.; 1766 orally (Betzing, 1982)

Synonyms & References

English

NSC759830
Tox21_500447
NCGC00186006-02
Nefiracetamum
Tox21_303025
MFCD00209882
AB01274721_02
DB13082
1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-2-oxo-
SMR001456240
KS-5226
NGHTXZCKLWZPGK-UHFFFAOYSA-N
SY052956
77191-36-7
DM-9384
NCGC00259465-01
DM 9384
N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide
HMS3261I16
MLS004774126
CCRIS 6729
N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide
CHEMBL260829
FT-0630853
DZL-221
Q6039388
MLS006010195
NSC 759830
NCGC00186006-01
Pharmakon1600-01502315
SW219212-1

MDL Number

MFCD00209882

Customs Code

2933790090

FAQ

What is N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7)?

N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) is a chemical compound with the formula C14H19NO3. It is a white crystalline solid characterized by its acetamide functional group and a pyrrolidinyl ring. The molecule is commonly used as a synthetic intermediate in pharmaceutical and chemical research due to its structural versatility and reactivity.

What are the main uses of N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7)?

N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) is primarily utilized in pharmaceuticals as a precursor for drug development, particularly in analgesic and anti-inflammatory compounds. It also serves industrial applications in polymer synthesis and chemical manufacturing. In research, it is employed as a building block for custom organic synthesis and functional group modification.

Is N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) safe?

N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) is considered hazardous due to its potential toxicity. Handling precautions include wearing protective gloves, goggles, and a lab coat, avoiding inhalation or skin contact, and using fume hoods. Safety standards recommend compliance with OSHA and EPA guidelines to ensure proper disposal and minimize health risks.

How should N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) be stored?

Store N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (CAS: 77191-36-7) in a cool, dry, and dark place at 2-8°C. Keep it in a sealed, airtight container to prevent moisture and light exposure. Avoid storage near heat sources or incompatible materials to maintain stability and safety compliance.