2,2,6,6-Tetramethylpiperidine

Basic Information

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CAS Number

768-66-1

Molecular Formula

C9H19N

Molecular Weight

141.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

-59°C

Boiling Point

152 °C

Density

0.837 g/mL at 25 °C

Water Solubility

MISCIBLE

Solubility

MISCIBLE

Refractive Index

n20/D 1.445(lit.)

SMILES

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CC1(C)CCCC(C)(C)N1

InChI

InChI=1S/C9H19N/c1-8(2)6-5-7-9(3,4)10-8/h10H,5-7H2,1-4H3

InChIKey

RKMGAJGJIURJSJ-UHFFFAOYSA-N

LogP

2.3171

pKa

11.07(at 25℃)

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

111

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 (6.1) Class 3 (6.1)

Sensitiveness

Air Sensitive

Synonyms & References

English

2,2,6,6-Tetramethylpiperidine
HTMP
TMP
2,2,6,6-tetramethyl-piperidin
Norpempidine
TETRAMETHYLPIPERIDINE
Piperidine, 2,2,6,6-tetramethyl-
2,2,6,6-tetramethylpiperidine(TEMP)
2,2,6,6-Tetramethylpiperidine (HTMP)
2,2,6,6-Tetramethylp
2.2.6.6-Tetramethylpiperidine
2,2,6,6-Me4piperidine
2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY
2,2,6,6-Tetramethylpeperidine
2,2,6,6-tetramethyl-piperidine
EINECS 212-199-3
PIPERIDINE,2,2,6,6-TETRAMETHYL
2,2,6,6-TETRAMETHYL PIPERIDINE
44N9S1YCFM
2,2,6,6 Tetramethyl piperidine
NSC102838
PubChem7259
2,6,6-Tetramethylpiperidine
KSC378A0J
2,2,6,6-tetramethylpiperdine
2,2,6,6-tetramethylpiperidin
2,2,6,6-teramethylpiperidine
2,2,6,6-tetrameth

MDL Number

MFCD00005985

Customs Code

29333999

FAQ

What is 2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1)?

2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) is a cyclic amine compound with the chemical formula C10H18N. It is known for its stability and low reactivity, making it a useful stabilizing agent in various chemical applications. The molecule features four methyl groups attached to a piperidine ring, contributing to its inertness and resistance to oxidation.

What are the main uses of 2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1)?

2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) is commonly used as a stabilizer in pharmaceuticals and organic chemistry. It helps prevent oxidation in sensitive compounds, is utilized in the synthesis of other chemicals, and serves as a protective agent in research settings. Its applications also extend to industrial processes where chemical stability is critical.

Is 2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) safe?

2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) is generally considered safe when handled properly. It has low toxicity and is not classified as a hazardous substance under most safety regulations. However, standard safety precautions should still be followed, such as wearing gloves and ensuring good ventilation, to minimize exposure during handling.

How should 2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) be stored?

2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1) should be stored in a cool, dry, and dark place to maintain stability. It is typically kept in a sealed container to prevent moisture ingress and contamination. Storage away from incompatible materials and in a well-ventilated area is recommended to ensure long-term preservation of its chemical properties.