Tetramethylpyrazine hydrochloride (1:1)

Basic Information

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CAS Number

76494-51-4

Molecular Formula

C8H13ClN2

Molecular Weight

172.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White powder

Boiling Point

192.7℃ at 760mmHg

Solubility

,Methanol

SMILES

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CC1=C(N=C(C(=N1)C)C)C.Cl

InChI

InChI=1S/C8H12N2.ClH/c1-5-6(2)10-8(4)7(3)9-5;/h1-4H3;1H

InChIKey

RQKFOGXUTRDQPB-UHFFFAOYSA-N

LogP

2.1320800000000006

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

87.8

Safety Information

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Storage Conditions

2-8℃

Synonyms & References

English

SCHEMBL583535
Ligustrazine hydrochloride [WHO-DD]
CCG-266378
Ligustrazine hydrochloride
tetramethylpyrazine hydrochloride
chuanxiongzine hydrochloride
2,3,5,6-tetramethylpyrazine;hydrochloride
AC-8350
7YYD00RL0S
2,3,5,6-tetramethylpyrazine,hydrochloride
Ligustrazine Hydrochloride ,(S)
EN300-7512774
DTXSID20997867
AS-16022
Pyrazine, tetramethyl-, hydrochloride
Tetrapyrazine HCl
MFCD01109103
PYRAZINE, TETRAMETHYL-, MONOHYDROCHLORIDE
Ligustrazine (hydrochloride)
CHEMBL1939729
FT-0651691
Ligustrazine HCl
Chuanxiongzine hydrochloride;Tetramethylpyrazine hydrochloride
UNII-7YYD00RL0S
s3775
AKOS006227644
2,3,5,6-tetramethylpyrazine hydrochloride
Tetramethylpyrazine--hydrogen chloride (1/1)
76494-51-4
126400-81-5
Tetramethylpyrazine HCl

MDL Number

MFCD08689942

Customs Code

2942000000

FAQ

What is Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4)?

Tetramethylpyrazine hydrochloride (1:1) is a chemical compound with the CAS number 76494-51-4. It is derived from tetramethylpyrazine, a pyrazine ring with four methyl groups, and is combined with hydrochloric acid in a 1:1 molar ratio. This salt form is typically a white crystalline solid, soluble in water, and exhibits properties related to its role as a neurotransmitter modulator and vasodilator in biological systems.

What are the main uses of Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4)?

Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4) is primarily used in pharmaceuticals as a precursor for drugs targeting cardiovascular health. It also serves in research for studying neuroprotective effects and is occasionally applied in food additives to enhance flavor or aroma. Industrial uses include chemical synthesis and as a component in specialized formulations.

Is Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4) safe?

Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4) is generally considered safe when handled according to standard chemical safety protocols. It is not classified as highly toxic, but direct skin or eye contact may cause irritation. Always follow safety data sheet guidelines, use appropriate PPE, and ensure proper ventilation to minimize risks during handling or experimentation.

How should Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4) be stored?

Tetramethylpyrazine hydrochloride (1:1) (CAS: 76494-51-4) should be stored in a cool, dry, and dark place, ideally below 25°C. Keep it in a sealed, airtight container to prevent moisture absorption and maintain stability. Avoid exposure to light and incompatible substances, and store in a well-ventilated area to ensure long-term preservation.