4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone | CAS No. 763113-06-0

4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone

Basic Information

CAS Number

763113-06-0

Molecular Formula

C24H24N4O3

Molecular Weight

416.48 g/mol

AD

Basic Physical Properties

c1ccc2c(c1)c(n[nH]c2=O)Cc3cccc(c3)C(=O)N4CCN(CC4)C(=O)C5CC5

InChI

InChI=1S/C24H24N4O3/c29-22-20-7-2-1-6-19(20)21(25-26-22)15-16-4-3-5-18(14-16)24(31)28-12-10-27(11-13-28)23(30)17-8-9-17/h1-7,14,17H,8-13,15H2,(H,26,29)

InChIKey

UMOUCKQSZGWWOH-UHFFFAOYSA-N

LogP

2.2083000000000004

Topological Polar Surface Area

86.37 Ų

Hydrogen Bond Donor/Acceptor

1 / 7

Synonyms & References

English

  • 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone
  • 4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)benzyl) phthalazin-1(2H)-one

FAQ

What are the physical and chemical properties of 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone (CAS: 763113-06-0)?

4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone is a crystalline compound with a high molecular weight and good solubility in organic solvents. It is moderately reactive, particularly towards nucleophiles and bases. The compound has a distinct melting point and is stable under normal conditions.

How is 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone (CAS: 763113-06-0) typically synthesized?

4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone is synthesized via a multi-step process involving condensation and coupling reactions. Commonly, it is prepared using piperazinyl derivatives and cyclopropylcarbonyl compounds under mild conditions with a catalyst. The synthesis typically yields up to 80% purity with good selectivity.

What industries use 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone (CAS: 763113-06-0)?

This compound is primarily used in the pharmaceutical industry for its potential in drug development, particularly in the synthesis of novel antiviral and anti-inflammatory agents. It is also considered for applications in sensors and semiconductors due to its structural complexity and electronic properties.

What precautions should be taken when handling 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone (CAS: 763113-06-0)?

When handling 4-(3-{[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl}benzyl)-1(2H)-phthalazinone, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store in a cool, dry place, away from incompatible materials. Handle in a well-ventilated area or fume hood to avoid inhalation. Follow standard laboratory safety protocols and consult the Safety Data Sheet (SDS) for detailed information.

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