N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine

Basic Information

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CAS Number

76265-69-5

Molecular Formula

C23H23F3N2O5

Molecular Weight

464.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

172-189°C

Boiling Point

668.3°C at 760 mmHg

Specific Rotation

-13° (c=1, in DMF)

SMILES

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C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCCNC(=O)C(F)(F)F)C(=O)O

InChI

InChI=1S/C23H23F3N2O5/c24-23(25,26)21(31)27-12-6-5-11-19(20(29)30)28-22(32)33-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,27,31)(H,28,32)(H,29,30)/t19-/m0/s1

InChIKey

ZVLMWTPNDXNXSZ-IBGZPJMESA-N

LogP

3.8271000000000015

Topological Polar Surface Area

104.73 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

680

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A-trifluoroacetyl-L-lysine
fmoc-lys(-tfa)-oh
AC-8598
Fmoc-N-epsilon-trifluoroacetyl-L-lysine
DTXSID00583803
N
MFCD00153360
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-(2,2,2-trifluoroacetamido)hexanoic acid
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine (Fmoc-L-Lys(TFA)-OH)
Fmoc-Nepsilon-trifluoroacetyl-L-lysine
A-Fmoc-N
Fmoc-Lys(Tfa)-OH, >=96.0% (HPLC)
Fmoc-Lys(Tfa)-OH
CS-W011546
SCHEMBL178772
ZVLMWTPNDXNXSZ-IBGZPJMESA-N
EN300-1556740
AMY22555
AS-14205
AKOS015909869
Fmoc-L-Lys(tfa)-OH
N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(2,2,2-trifluoroacetyl)-L-lysine
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2,2,2-trifluoroacetyl)amino]hexanoic acid
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-6-(trifluoroacetamido)hexanoic acid
M03423
N~2~-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-N~6~-(trifluoroacetyl)-L-lysine
HY-W010830
F11032
76265-69-5
N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-trifluoracetyl-L-lysine
Nα-Fmoc-Nε-trifluoroacetyl-L-lysine

MDL Number

MFCD00153360

Customs Code

29242990

FAQ

What regulatory guidelines apply to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5) should comply with GHS classification for hazardous chemicals, and is subject to REACH regulations in the European Union. In the United States, FDA and EPA regulations may apply depending on the intended use. It is advisable to consult the latest regulatory requirements for specific applications.

Are there alternatives to N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5) in synthesis?

Alternative reagents for synthesizing similar functional groups include other amino acid derivatives or protected amino acids. Isomers or analogs, such as different protected amino acids or related fluorenylmethoxycarbonyl (FMOC) protected amino acids, can be considered based on the specific needs and reactivity requirements of the synthesis.

What is the market or research trend for N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5)?

The market for N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5) is driven by its applications in peptide synthesis and pharmaceutical research. Recent research trends focus on its use in developing novel drug candidates and therapeutic peptides. Market demand is expected to grow with advancements in biotechnology and pharmaceuticals.

How should waste containing N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5) be handled?

Waste containing N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-(trifluoroacetyl)-L-lysine (CAS: 76265-69-5) should be collected in appropriate containers and disposed of through professional waste disposal services to ensure compliance with environmental regulations. Incineration or other safe disposal methods should be employed to minimize environmental impact. Always consult local regulations and environmental protection guidelines for specific disposal procedures.