3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine | CAS No. 762240-92-6

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine

Basic Information

CAS Number

762240-92-6

Molecular Formula

C6H7F3N4

Molecular Weight

228.61 g/mol

AD

Basic Physical Properties

Melting Point

236-246°C

Flash Point

114.8℃

C1CN2C(=NN=C2C(F)(F)F)CN1.Cl

InChI

InChI=1S/C6H7F3N4/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5/h10H,1-3H2

InChIKey

FMTDZGCPYKWMPT-UHFFFAOYSA-N

LogP

0.8218999999999999

Topological Polar Surface Area

42.74 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

195

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H332 Harmful if inhaled
Acute toxicity, inhalation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine HCl
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine;hydrochloride
  • Y0OF5KV5KA
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-alpha]pyrazine, hydrochloride salt
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazinehydrochloride
  • 3-trifluoromethyl-[1,2,4]triazole[4,3-a]piperazinehydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine--hydrogen chloride (1/1)
  • 3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride
  • 3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine hydrochloride, AldrichCPR
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-alpha]pyrazine hydrochloride
  • 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-
  • Sitagliptin Triazole Hydrochloride
  • 1,2,4-TRIAZOLO(4,3-A)PYRAZINE, 5,6,7,8-TETRAHYDRO-3-(TRIFLUOROMETHYL)-, HYDROCHLORIDE (1:1)
  • CS-M0692
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride
  • HY-76120
  • Sitagliptin intermediate A
  • 3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine Hydrochloride
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
  • AKOS005063627
  • AC-2623
  • PB32770
  • AM20100748
  • MFCD09817638
  • 3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloric acid
  • SCHEMBL332198
  • RB3135
  • NS00078443
  • SY002323
  • Sitagliptin Impurity 18

MDL Number

MFCD09817638

Customs Code

2933990090

FAQ

What is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6)?

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) is a heterocyclic compound containing a pyrazine ring fused with a triazolopyrazine structure. It is characterized by the presence of a trifluoromethyl group attached to the pyrazine ring, making it a valuable intermediate in organic synthesis. This compound is known for its stability and reactivity in various chemical environments, often used in the development of pharmaceuticals and other specialized chemical applications.

What are the main uses of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6)?

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) is primarily used as a key intermediate in the synthesis of pharmaceutical compounds, particularly those targeting neurological and metabolic disorders. It also finds applications in chemical research for developing new drugs and materials, and in industrial processes for creating specialized derivatives with enhanced functional properties.

Is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) safe?

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) is generally considered safe when handled properly. However, as with many organic compounds, it should be used with appropriate safety measures, including protective gloves, goggles, and ventilation. It is advisable to follow standard chemical safety protocols to minimize exposure and ensure safe handling in laboratory and industrial settings.

How should 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) be stored?

3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine (CAS: 762240-92-6) should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It is recommended to keep it in airtight containers to prevent moisture and contamination. Avoid exposure to light and ensure storage in a well-ventilated area to maintain stability and prolong shelf life.

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