Ramoplanin | CAS No. 76168-82-6

Ramoplanin

Basic Information

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CAS Number

76168-82-6

Molecular Formula

C25H40N6O7

Molecular Weight

536.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

210-230°

Specific Rotation

D20 +78.3° (c = 1.04 in H2O)

SMILES

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CCCC=CC=CC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC)C1CCC(CC1)O)CC(=O)N)CC(=O)N

InChI

InChI=1S/C25H40N6O7/c1-3-4-5-6-7-8-21(35)29-17(13-19(26)33)23(36)30-18(14-20(27)34)24(37)31-22(25(38)28-2)15-9-11-16(32)12-10-15/h5-8,15-18,22,32H,3-4,9-14H2,1-2H3,(H2,26,33)(H2,27,34)(H,28,38)(H,29,35)(H,30,36)(H,31,37)

InChIKey

YJNHGEDGQOEGCY-UHFFFAOYSA-N

LogP

-1.5987999999999944

Topological Polar Surface Area

222.81 Å²

Hydrogen Bond Donor/Acceptor

9 / 13

Safety Information

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Toxicity

LD50 in mice (mg/kg): 328 i.p., 122 i.v.; orally in rats: 2000 mg/kg (Pallanza)

Synonyms & References

English

A 16686
A 16686A
Antibiotic A 16686
RaMoplanin(A 16686,A 16686A)
RaMoplanin coMplex
Ramoplanin
Ramoplaninr
Ray mora ning
Ramipril Methyl-d3 Ester
Antibiotic A 16686, 2-(((3alpha,5beta)-3-hydroxy-7,24-dioxocholan-24-yl)amino)-, (SP-4-2)-
Glycolipodepsi peptide
Glycolipodepsi peptide antibiotic produced by actinoplanes species ATCC33076. Ramoplanin is a complex antibiotic consisting of a main component designated as ramoplanin A2 and a small amount of related substances, ramoplanin A1, A'1, A'2, A3, and A'3
MDL 62,198
Ramoplanin [USAN:INN]

MDL Number

MFCD01775776

FAQ

What is Ramoplanin (CAS: 76168-82-6)?

Ramoplanin is a glycopeptide antibiotic with a unique chemical structure. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against certain gram-positive pathogens. Ramoplanin has a chemical formula of C41H75NO18 and exhibits properties such as stability against β-lactamases.

What are the main uses of Ramoplanin (CAS: 76168-82-6)?

Ramoplanin is primarily used in the treatment of infections caused by gram-positive bacteria, particularly those resistant to other antibiotics. It is approved for use in clinical settings to address infections such as skin and soft tissue infections, as well as in combination therapy for certain infections.

Is Ramoplanin (CAS: 76168-82-6) safe?

Ramoplanin is generally considered safe when used as directed. However, like all antibiotics, it may cause side effects such as gastrointestinal discomfort. Precautions include monitoring for signs of allergic reactions, and it should not be used in patients with a known history of hypersensitivity to similar antibiotics.

How should Ramoplanin (CAS: 76168-82-6) be stored?

Ramoplanin should be stored at a temperature between 2°C and 8°C (36°F to 46°F) in its original container. It should be protected from light and stored in a secure, dry place. Avoid exposing the compound to extremes of temperature and humidity to maintain its efficacy and stability.