2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide | CAS No. 761436-81-1

2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide

Basic Information

CAS Number

761436-81-1

Molecular Formula

C23H28BrN7O3S

Molecular Weight

562.49 g/mol

AD

Basic Physical Properties

CNS(=O)(=O)c1ccccc1Nc2c(cnc(n2)Nc3ccc(cc3OC)N4CCN(CC4)C)Br

InChI

InChI=1S/C23H28BrN7O3S/c1-25-35(32,33)21-7-5-4-6-19(21)27-22-17(24)15-26-23(29-22)28-18-9-8-16(14-20(18)34-3)31-12-10-30(2)11-13-31/h4-9,14-15,25H,10-13H2,1-3H3,(H2,26,27,28,29)

InChIKey

FTSDLONCFCQDGA-UHFFFAOYSA-N

LogP

3.394800000000002

Topological Polar Surface Area

111.72 Ų

Hydrogen Bond Donor/Acceptor

3 / 10

Complexity

765

Synonyms & References

English

  • ALK inhibitor 1
  • 2-[[5-bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide
  • Benzenesulfonamide, 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-
  • C23H28BrN7O3S
  • BCP28167
  • 3433AH
  • A14987
  • 2-({5-Bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl}amino)-N-methylbenzene-1-sulfonamide
  • 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzenesulfonamide

MDL Number

MFCD23380588

FAQ

What is 2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1)?

2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) is a complex organic compound with potential pharmaceutical applications. It is derived from a combination of aromatic and heterocyclic structures, making it suitable for use in medicinal chemistry and drug development.

What are the main uses of 2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1)?

2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) is primarily used in the pharmaceutical industry for research and development of novel therapeutics, particularly in the treatment of various diseases. It may also be used in academic and industrial settings for drug screening and lead molecule development.

Is 2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) safe?

2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) is safe when handled under appropriate laboratory conditions. However, it should be used with caution and proper personal protective equipment (PPE) due to its potential irritant and reactive properties. Follow all safety guidelines and consult the Material Safety Data Sheet (MSDS) for specific precautions.

How should 2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) be stored?

2-[(5-Bromo-2-{[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)amino]-N-methylbenzenesulfonamide (CAS: 761436-81-1) should be stored in a cool, dry place away from direct sunlight and heat sources. It is recommended to keep the compound in a tightly sealed container to maintain its stability. Store it at room temperature (15-25°C) and avoid exposure to moisture and air to prevent degradation.

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