2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole

Basic Information

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CAS Number

760212-40-6

Molecular Formula

C19H13BrN2

Molecular Weight

349.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

123.0 to 127.0 deg-C

Boiling Point

513.6 ℃ at 760 mmHg

Density

1.38

Flash Point

264.4°C

Refractive Index

1.671

SMILES

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C1=CC=C(C=C1)N2C3=CC=CC=C3N=C2C4=CC(=CC=C4)Br

InChI

InChI=1S/C19H13BrN2/c20-15-8-6-7-14(13-15)19-21-17-11-4-5-12-18(17)22(19)16-9-2-1-3-10-16/h1-13H

InChIKey

YFUWVSPCUFTGQN-UHFFFAOYSA-N

LogP

5.455000000000004

Topological Polar Surface Area

17.82 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

368

Synonyms & References

English

SY038956
B4794
FT-0656594
MFCD12911655
2-(3-bromophenyl)-1-phenylbenzimidazole
AS-30147
DTXSID40630567
A838588
SCHEMBL338639
760212-40-6
2-(3-Bromophenyl)-1-phenyl-1H-benzoimidazole
AKOS015901373
CS-0156111
1H-Benzimidazole, 2-(3-bromophenyl)-1-phenyl-
2-(3-bromophenyl)-1-phenyl-1H-benzo[d]imidazole
2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole
2-(3-bromophenyl)-1-phenyl-1H-1,3-benzodiazole
YFUWVSPCUFTGQN-UHFFFAOYSA-N
2-(3-Bromophenyl)-1-phenylbenzimidazole
1H-Benzimidazole,2-(3-bromophenyl)-1-phenyl-
2-(3-BROMOPHENYL)-1-PHENYL-1H-BENZIMIDAZOLE
zlchem 648
ZLD0098
1825AC
EBD709928
LS40629
VI10086
2-(

MDL Number

MFCD12911655

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole (CAS: 760212-40-6)?

2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole is a crystalline solid with a molecular weight of approximately 335.02 g/mol. It has low aqueous solubility and good solubility in organic solvents like dimethylformamide and dichloromethane. This compound is not highly reactive, but it can undergo substitution reactions under certain conditions. It is characterized by its UV-Vis absorption in the 250-350 nm range and its low reactivity with common reagents.

How is 2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole (CAS: 760212-40-6) typically synthesized?

2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole is synthesized via a multi-step process involving reactions such as bromination and subsequent condensation. The synthesis typically involves bromination of a phenyl group, followed by coupling with a benzimidazole derivative. Common catalysts include bases like triethylamine, and solvents like dichloromethane are often used. The yield is generally around 70-80%, depending on the purity of the starting materials and the optimization of reaction conditions.

What industries use 2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole (CAS: 760212-40-6)?

2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole finds applications in pharmaceuticals, particularly in the development of potential anticancer drugs due to its structural similarity to other active compounds. It is also used in the synthesis of certain dyes and pigments. Additionally, it has potential uses in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs), and as a building block in the synthesis of functional polymers.

What precautions should be taken when handling 2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole (CAS: 760212-40-6)?

When handling 2-(3-Bromophenyl)-1-phenyl-1H-benzimidazole, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood to minimize exposure to airborne particles. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines. Proper storage should be in a cool, dry place away from direct sunlight and heat sources.