N-Methylformic hydrazide | CAS No. 758-17-8

N-Methylformic hydrazide

Basic Information

CAS Number

758-17-8

Molecular Formula

C2H6N2O

Molecular Weight

74.08 g/mol

AD

Basic Physical Properties

Boiling Point

131.34°C (rough estimate)

Density

1.0968 (rough estimate)

Refractive Index

1.4368 (estimate)

CN(C=O)N

InChI

InChI=1S/C2H6N2O/c1-4(3)2-5/h2H,3H2,1H3

InChIKey

RSFOTOSOKJMMCB-UHFFFAOYSA-N

LogP

-1.0517

Topological Polar Surface Area

46.33 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

36.6

Synonyms & References

English

  • D74578
  • N-METHYL-N-FORMYLHYDRAZINE
  • 3L13R06H7D
  • N-Methylformohydrazide
  • NSC122452
  • C2H6N2O
  • N-METHYL-N-FORMYLHYDRAZINE [HSDB]
  • CS-0084846
  • 758-17-8
  • Formic acid, methylhydrazide
  • BRN 2036827
  • 2-Methyl-2-formylhydrazine
  • NSC 122452
  • SY338851
  • Hydrazine, 1-formyl-1-methyl-
  • DTXSID2020840
  • Hydrazinecarboxaldehyde, 1-methyl-
  • N-methylformic hydrazide
  • 1-Methyl-1-formylhydrazine
  • Methylformylhydrazine
  • 1-METHYLHYDRAZINECARBOXALDEHYDE
  • Q27257474
  • 1-Methyl-1-formylhydrazide
  • CCRIS 1182
  • N-Formyl-N-methylhydrazine
  • RSFOTOSOKJMMCB-UHFFFAOYSA-N
  • MFH
  • N-amino-N-methylformamide
  • Formic acid, 1-methylhydrazide
  • HSDB 3510
  • 1-Methylformylhydrazine

MDL Number

MFCD01726298

FAQ

What are the physical and chemical properties of N-Methylformic hydride (CAS: 758-17-8)?

N-Methylformic hydride (CAS: 758-17-8) is a crystalline solid at room temperature with a molecular weight of approximately 83.07 g/mol. It is sparingly soluble in water but highly soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in its ability to undergo nucleophilic substitution reactions.

How is N-Methylformic hydride (CAS: 758-17-8) typically synthesized?

N-Methylformic hydride (CAS: 758-17-8) is typically synthesized through the reaction of methyl formate with sodium hydride. The reaction is carried out in a solvent such as methanol, and the process involves careful control of temperature and stirring to ensure high selectivity and yield. This method requires the use of appropriate catalysts and safety measures to handle the reactive intermediates.

What industries use N-Methylformic hydride (CAS: 758-17-8)?

N-Methylformic hydride (CAS: 758-17-8) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for the modification of organic materials, sensors for detecting specific chemicals, and semiconductors for the doping process. Its reactivity makes it valuable in organic synthesis.

What precautions should be taken when handling N-Methylformic hydride (CAS: 758-17-8)?

When handling N-Methylformic hydride (CAS: 758-17-8), it is crucial to use Personal Protective Equipment (PPE) including gloves, goggles, and a laboratory coat. Handle in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling guidelines.

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