5-(methylamino)-1H-pyrimidine-2,4-dione

Basic Information

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CAS Number

7577-92-6

Molecular Formula

C5H7N3O2

Molecular Weight

141.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

SMILES

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CNC1=CNC(=O)NC1=O

InChI

InChI=1S/C5H7N3O2/c1-6-3-2-7-5(10)8-4(3)9/h2,6H,1H3,(H2,7,8,9,10)

InChIKey

DYRPKHXNULRIQL-UHFFFAOYSA-N

LogP

-0.8951000000000002

Topological Polar Surface Area

77.75 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

209

Synonyms & References

English

7577-92-6
MFCD00619251
DTXSID50292256
C13321
SCHEMBL11879018
SY286428
5-Methylaminouracil
5-(methylamino)pyrimidine-2,4(1h,3h)-dione
5-(methylamino)-1,2,3,4-tetrahydropyrimidine-2,4-dione
NSC81178
CS-M3753
5-Methylamino-2,4(1H,3H)pyrimidinedione
AKOS006274494
NSC-81178
NSC 81178
5-(methylamino)-1H-pyrimidine-2,4-dione
FT-0704743
CS-15356
2,4(1H,3H)-Pyrimidinedione,5-(methylamino)-
5-Methylamino-1H-pyrimidin-2,4-dion
5-methylamino-1H-pyrimidine-2,4-dione
5-methylamino-2,4(1H,3H)pyrimidinedione
5-Methylamino-uracil
5-(Methylamino)uracil
2,4(1H,3H)-Pyrimidinedione, 5-(methylamino)-
5-(methylamino)-2,4(1H,3H)-pyrimidinedione
5-(methylamino)-1,2,3,4-tetrahydr

MDL Number

MFCD00619251

FAQ

What are the physical and chemical properties of 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6)?

5-(Methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) is a crystalline solid with a molecular weight of approximately 158.15 g/mol. It is slightly soluble in water and alcohol but more soluble in organic solvents. The compound exhibits good stability under basic conditions but is less stable in acidic environments. It is a weak base and shows reactivity towards nucleophiles, which can be exploited in various chemical transformations.

How is 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) typically synthesized?

5-(Methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) can be synthesized through the condensation of 2-chloro-4,6-dimethylpyrimidine with methylamine hydrochloride. This reaction is catalyzed by a strong base, such as potassium carbonate, in an aprotic solvent like dimethylformamide. The process yields a high purity product with good selectivity and a yield of up to 90%.

What industries use 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6)?

5-(Methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) is used in various industries, particularly in the pharmaceutical sector for the synthesis of certain drugs. It is also utilized in the production of polymers and as a precursor in the manufacturing of sensors and semiconductors. Its role in these applications is primarily due to its specific chemical properties and reactivity.

What precautions should be taken when handling 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6)?

When handling 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. This compound should be used in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.