Compound Q&A
How is 5-(methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) typically synthesized?
Answer
5-(Methylamino)-1H-pyrimidine-2,4-dione (CAS: 7577-92-6) can be synthesized through the condensation of 2-chloro-4,6-dimethylpyrimidine with methylamine hydrochloride. This reaction is catalyzed by a strong base, such as potassium carbonate, in an aprotic solvent like dimethylformamide. The process yields a high purity product with good selectivity and a yield of up to 90%.
About
CAS No
7577-92-6
English Name
5-(methylamino)-1H-pyrimidine-2,4-dione
Molecular Formula
C5H7N3O2
Molecular Weight
141.13 g/mol
SMILES
CNC1=CNC(=O)NC1=O
InChIKey
DYRPKHXNULRIQL-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59
