Nilvadipine | CAS No. 75530-68-6

Nilvadipine

Basic Information

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CAS Number

75530-68-6

Molecular Formula

C19H19N3O6

Molecular Weight

385.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

149.0 to 153.0 deg-C

Boiling Point

519.3°C at 760 mmHg

Density

1.3937 (rough estimate)

Flash Point

253.0±28.7 °C

Solubility

DMSO: soluble15mg/mL, clear

Refractive Index

1.5900 (estimate)

Vapor Pressure

0.0±1.3 mmHg at 25°C

SMILES

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CC1=C(C(C(=C(N1)C#N)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C

InChI

InChI=1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3

InChIKey

FAIIFDPAEUKBEP-UHFFFAOYSA-N

LogP

3.30988

Complexity

783

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

SK&F-102362
CL-287,389
FK 235
Nivadip
AB01566895_01
5-Isopropyl 3-Methyl 2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
O3-methyl O5-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-
3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
HY-14284
Escor
CAS-75530-68-6
0214FUT37J
N0899
nilvadipine
NCGC00167435-02
75530-68-6
BDBM50103634
Nilvadipine (ARC029)
BCP06007
Nilvadipine (JP17/USAN/INN)
SW219572-1
NS00003603
GTPL10160
FK-235
5-isopropyl 3-methyl (+)-2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
NCGC00167435-01
KS-1303
3-methyl 5-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
AC-28326
CCG-220648
ARC029

MDL Number

MFCD00867065

FAQ

What is Nilvadipine (CAS: 75530-68-6)?

Nilvadipine is a calcium channel blocker used in the treatment of hypertension and angina. It is a white or off-white crystalline powder with a molecular formula of C25H29NO4 and a molecular weight of 417.54. Nilvadipine is known for its oral bioavailability and its ability to exert its effect on vascular smooth muscle relaxation.

What are the main uses of Nilvadipine (CAS: 75530-68-6)?

Nilvadipine is primarily used as an antihypertensive drug to lower blood pressure and as a vasodilator for the treatment of angina pectoris. It can also be used in the prevention of migraines and in the management of other cardiovascular conditions.

Is Nilvadipine (CAS: 75530-68-6) safe?

Nilvadipine is generally considered safe when used as prescribed. However, it may cause side effects such as headache, dizziness, and swelling of the ankles. Patients should be monitored for signs of allergic reactions and other adverse effects. It is important to follow the recommended dosage and consult a healthcare provider if any concerns arise.

How should Nilvadipine (CAS: 75530-68-6) be stored?

Nilvadipine should be stored at a temperature not exceeding 25°C and should be protected from light. The drug should be kept in a tightly closed container to prevent moisture and ensure its stability. It is advisable to store it in a cool, dry place away from direct sunlight and heat sources.