5-Iodo-6-methyl-2-pyridinamine

Basic Information

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CAS Number

75073-11-9

Molecular Formula

C6H7IN2

Molecular Weight

234.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

99.9-100.1°C

Boiling Point

287℃ at 760 mmHg

SMILES

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CC1=C(C=CC(=N1)N)I

InChI

InChI=1S/C6H7IN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)

InChIKey

AFMNJDHAAFAELF-UHFFFAOYSA-N

LogP

1.5768199999999999

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Light Sensitive

Synonyms & References

English

5-Iodo-6-methylpyridin-2-amine
MFCD04138418
FT-0646519
BS-2100
AFMNJDHAAFAELF-UHFFFAOYSA-N
HMS1783F06
75073-11-9
O-DESMETHYLERLOTINIB-D8HCL
SY013205
5-iodo-6-methylpyridin-2-amine;6-Amino-3-iodo-2-methylpyridine
AKOS000108858
EN300-101241
DTXSID90359332
5-IODO-6-METHYL-2-PYRIDINAMINE
5-iodo-6-methylpyridine-2-amine
5-Iodo-6-methyl-pyridin-2-ylamine
CS-W012918
AC-23493
2-AMINO-5-IODO-6-PICOLINE
6-Amino-3-iodo-2-methylpyridine
AB20800
W-203720
Z57296056
5-Iodo-6-methyl-pyridin-2-ylamine, AldrichCPR
5-Iodo-6-methyl-pyridin-ylamine
A9582
2-AMINO-5-IODO-6-METHYLPYRIDINE
2-Pyridinamine, 5-iodo-6-methyl-
SCHEMBL503306
BB 0245402
5-IODO-6-METHYL-PYRIDIN-2-YLAMINE

MDL Number

MFCD00051795

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9)?

5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9) is a crystalline solid with a molecular weight of approximately 231.04 g/mol. It has a solubility of 0.001 g/100 mL in water at 25°C. It is moderately reactive, especially towards nucleophilic substitution reactions at the iodine atom.

How is 5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9) typically synthesized?

5-Iodo-6-methyl-2-pyridinamine can be synthesized via a multi-step process from 6-methyl-2-pyridinamine. The iodination step typically requires an aryl iodide reagent and a base under anhydrous conditions. The reaction yields 5-Iodo-6-methyl-2-pyridinamine with high selectivity.

What industries use 5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9)?

5-Iodo-6-methyl-2-pyridinamine is used in the pharmaceutical industry for the synthesis of various drug intermediates. It is also utilized in the polymer industry for the modification of polymer properties and in the sensor industry for the development of chemical sensors and detectors.

What precautions should be taken when handling 5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9)?

When handling 5-Iodo-6-methyl-2-pyridinamine (CAS: 75073-11-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or a fume hood. Follow standard safety procedures and consult the Material Safety Data Sheet (MSDS) for detailed information on storage and disposal.