Region: EU • Category: SVHC高度关注物质

Date: 2018-01-15 • Reason: REACH SVHC Candidate List - 致癌物质

Oxirane | CAS No. 75-21-8

Oxirane

Basic Information

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CAS Number

75-21-8

Molecular Formula

C2H4O

Molecular Weight

44.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

148.5-149.5 ºC

Boiling Point

183-192 ºC (0.15 Torr)

Density

1.1238 g/cm3 (15 ºC)

Flash Point

-49.0±15.3 ºC,

Refractive Index

1.4840 (589.3 nm 15 ºC)

SMILES

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C1CO1

InChI

InChI=1S/C2H4O/c1-2-3-1/h1-2H2

InChIKey

IAYPIBMASNFSPL-UHFFFAOYSA-N

LogP

0.016600000000000004

Topological Polar Surface Area

12.53 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

10.3

Safety Information

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GHS Hazard Pictograms

H224

H301

H319

H330

Hazard Statement

H224 Extremely flammable liquid and vapor
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H330 Fatal if inhaled
Acute toxicity, inhalation

Hazard Class

Class 2.3 Class 2.3

Synonyms & References

English

.alpha.,.beta.-Oxidoethane
oxyde d'ethylene
Oxirene, Dihydro-
E0692
ETHYLENE OXIDE [IARC]
AI3-26263
RCRA waste no. U115
AKOS009031564
ETO
Oxirane
CHEMBL1743219
HSDB 170
c0527
Oxiranyl
NS00005032
Aethylenoxid
1,2-Epoxyaethan [German]
Oxiraan
Oxyfume
ethylene-oxide
CCRIS 297
ETHYLENE OXIDE [FHFI]
ETHYLENE OXIDE
Oxidoethane
Ethylene oxide 10000 microg/mL in Dimethylsulfoxide
Oxiraan [Dutch]
D03474
Ethyleenoxide [Dutch]
Dihydrooxirene
Caswell No. 443
epoxy ethane

MDL Number

MFCD00014482

Customs Code

2910100000

FAQ

What are the physical and chemical properties of Oxirane (CAS: 75-21-8)?

Oxirane, also known as epoxyethane, has a molecular weight of 44.05 g/mol and is a colorless to slightly yellowish gas at room temperature. It has a boiling point of 3.7°C and a melting point of -111.5°C. Oxirane is highly soluble in water and ether. It is a reactive compound, readily participating in addition and substitution reactions.

How is Oxirane (CAS: 75-21-8) typically synthesized?

Oxirane is typically synthesized by the oxidation of ethylene. A common method involves the reaction of ethylene with oxygen in the presence of a metal catalyst, such as silver. The process requires careful control of temperature and pressure to achieve high selectivity and yield.

What industries use Oxirane (CAS: 75-21-8)?

Oxirane is widely used in the pharmaceutical, polymer, and semiconductor industries. In pharmaceuticals, it is used as a building block for the synthesis of various drugs. In polymers, it is used to produce epoxy resins that are used in coatings, adhesives, and composites. In semiconductors, oxirane derivatives are used in the manufacture of photolithographic resists and protective coatings.

What precautions should be taken when handling Oxirane (CAS: 75-21-8)?

Proper precautions must be taken when handling oxirane. It should be handled in a fume hood, and personal protective equipment such as gloves, goggles, and protective clothing should be worn. Spills should be cleaned up immediately with appropriate absorbents. Safety data sheets (SDS) should be consulted for detailed information on handling and emergency procedures. Oxirane is highly reactive and can be toxic if inhaled or ingested. Storage should be in a cool, well-ventilated area away from sources of ignition and incompatible materials.