Formamide | CAS No. 75-12-7

Formamide

Basic Information

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CAS Number

75-12-7

Molecular Formula

CH3NO

Molecular Weight

45.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

2-3 °C

Boiling Point

210 °C

Density

1.134 g/mL at 25 °C

Water Solubility

miscible

Solubility

H2O: 10 M at 20 °C, clear, colorless

Refractive Index

n20/D 1.447(lit.)<br />n20/D 1.447

Vapor Pressure

0.08 mmHg ( 20 °C)<br />30 mmHg ( 129 °C)

SMILES

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NC=O

InChI

InChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChIKey

ZHNUHDYFZUAESO-UHFFFAOYSA-N

LogP

-0.8985000000000001

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

12.3

Safety Information

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Hazard Statement

Sensitiveness

Hygroscopic

Explosive Limit

2.7-19.0%(V)

Toxicity

LD50 in mice, rats (g/kg): 4.6, 5.7 i.p. (Pham-Huu-Chanh)

Synonyms & References

English

Formamide
Formamide Methanamide
Formamide, Molecular Biology Grade Methanamide, Molecular Biology Grade
Formamide, MB Grade (1.12017)
FORMAMIDE HDPE
FORMAMIDE, MOLECULAR BIOLOGY GRADE
FORMAMIDE, DEIONIZED
AMide C1
formamidic acid
ForMic acid aMide
formic-d acid,potassium salt
formimidic acid
Formimidsaeure
ForMylaMide
Hydroxyformaldimin
Kalium-d-formiat
potassium deuteroformate
Potassium formate-d
Formamide in dimethyl sulfoxide
Carbamaldehyde
Methanamide
NSC 748
甲酰胺
Formic acid, amide
formamid
Methanoic acid, amide
Amid kyseliny mravenci
Amid kyseliny mravenci [Czech]
Formic amide
HCONH2
Carbamaldehyde, Methanamide

MDL Number

MFCD00007941

Customs Code

2924199090

FAQ

What is Formamide (CAS: 75-12-7)?

Formamide, with the CAS number 75-12-7, is a simple organic compound with the chemical formula CH3NO. It is a colorless, hygroscopic liquid that is miscible with water and many organic solvents. Formamide is known for its ability to act as both a hydrogen bond donor and acceptor, making it useful in various chemical reactions. It has a mild, ammonia-like odor and is commonly used in industrial and laboratory settings due to its versatile chemical properties.

What are the main uses of Formamide (CAS: 75-12-7)?

Formamide (CAS: 75-12-7) is widely used in pharmaceuticals as a solvent and intermediate in drug synthesis. It also serves as a raw material in the production of resins, dyes, and pesticides. In research, it is employed in peptide synthesis and as a reagent in analytical chemistry. Additionally, it is used in the textile industry for dyeing processes and in the formulation of some food products as a processing aid, though it is not directly consumed.

Is Formamide (CAS: 75-12-7) safe?

Formamide (CAS: 75-12-7) is generally considered safe when handled properly, but it can be harmful if inhaled, ingested, or exposed to skin. It is classified as a toxic substance with potential irritant effects. Safety standards recommend using appropriate personal protective equipment (PPE) such as gloves and goggles. Proper ventilation and safe disposal are essential to minimize health and environmental risks.

How should Formamide (CAS: 75-12-7) be stored?

Formamide (CAS: 75-12-7) should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is best kept in a sealed, non-corrosive container made of glass or polyethylene. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability. Avoid contact with strong oxidizers or acids to prevent degradation or hazardous reactions.