2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine

Basic Information

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CAS Number

74901-71-6

Molecular Formula

C6H4Cl2N2S

Molecular Weight

207.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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Clc1nc2CSCc2c(Cl)n1

InChI

InChI=1S/C6H4Cl2N2S/c7-5-3-1-11-2-4(3)9-6(8)10-5/h1-2H2

InChIKey

YSADLUWHNVZEJK-UHFFFAOYSA-N

LogP

2.5302000000000007

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Synonyms & References

English

2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine
2,4-dichloro-5H,7H-thieno[3,4-d]pyrimidine

MDL Number

MFCD13250061

FAQ

What are the physical and chemical properties of 2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine (CAS: 74901-71-6)?

2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine is a crystalline compound with a molecular weight of approximately 214.02 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. It is moderately reactive and can undergo nucleophilic substitution reactions. The compound is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is 2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine (CAS: 74901-71-6) typically synthesized?

2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine can be synthesized through the reaction of 2,4-dichloropyrimidine with thiophene. The synthesis involves heating the reactants in a suitable solvent under mild conditions, followed by work-up procedures such as extraction and recrystallization to obtain the desired product. The process typically yields a high purity product with good selectivity.

What industries use 2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine (CAS: 74901-71-6)?

2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the development of novel materials. Additionally, it can be used in the sensor and semiconductor industries for various analytical and electronic applications.

What precautions should be taken when handling 2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine (CAS: 74901-71-6)?

When handling 2,4-Dichloro-5,7-dihydrothieno[3,4-d]pyrimidine, it is important to use proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.