4-[4-(4-Aminophenyl)-1-piperazinyl]phenol

Basic Information

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CAS Number

74853-08-0

Molecular Formula

C16H19N3O

Molecular Weight

269.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

532.8°C at 760 mmHg

SMILES

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OC1=CC=C(N2CCN(C3=CC=C(N)C=C3)CC2)C=C1

InChI

InChI=1S/C16H19N3O/c17-13-1-3-14(4-2-13)18-9-11-19(12-10-18)15-5-7-16(20)8-6-15/h1-8,20H,9-12,17H2

InChIKey

WZIJMPVPOMTRNM-UHFFFAOYSA-N

LogP

2.301

Topological Polar Surface Area

52.730000000000004 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
4-(4-(4-AMINOPHENYL)-1-PIPERZINYL)PHENOL
4-HYDROXYPHENYLAMINOPHENYLPIPERAZINE
4-[4-(4-aMinophenyl)piperazin-1-yl]phenol
Phenol, 4-[4-(4-aMinophenyl)-1-piperazinyl]-
POSACONZOLE INTERMEDIATE
4-[4-(4-aMinophenyl)piperazino]phenol
1-(4-AMINOPHENYL)-4-(4-HYDROXYPHENYL) PIPERZINE
Posaconazole Impurity 28

MDL Number

MFCD02093082

Customs Code

2933599090

FAQ

What is 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0)?

4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) is a chemical compound containing a phenol ring substituted with a piperazine group linked to a 4-aminophenyl moiety. Its molecular formula is C16H21N3O. It is known for its aromatic and amine functionalities, which may contribute to its biological activity and reactivity in chemical reactions.

What are the main uses of 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0)?

4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) is primarily used in pharmaceutical research as a potential drug candidate for treating neurological disorders. It may also serve as an intermediate in organic synthesis for developing compounds in materials science and chemical research. Its unique structure makes it relevant for applications involving molecular targeting and medicinal chemistry.

Is 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) safe?

Safety of 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) depends on exposure conditions. It may exhibit mild toxicity upon contact with skin or eyes, and inhalation risks are possible. Proper handling with protective equipment (gloves, goggles, lab coat) is recommended. Always follow safety data sheet guidelines and ensure controlled environments to minimize hazards.

How should 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) be stored?

4-[4-(4-Aminophenyl)-1-piperazinyl]phenol (CAS: 74853-08-0) should be stored in a cool, dry place away from light. Maintain storage temperature between 2-8°C and keep humidity levels low to prevent degradation. Use airtight, dark-colored containers to protect stability. Avoid exposure to air and store away from incompatible substances for optimal preservation.