5-Methyl-3-nitro-2(1H)-pyridinone

Basic Information

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CAS Number

7464-14-4

Molecular Formula

C6H6N2O3

Molecular Weight

154.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

179 °C (dec.)

Boiling Point

353.3 °C at 760 mmHg

Density

1.24 g/mL at 25 °C

Flash Point

167.4 °C

Refractive Index

1.567

SMILES

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CC1=CNC(=O)C(=C1)[N+](=O)[O-]

InChI

InChI=1S/C6H6N2O3/c1-4-2-5(8(10)11)6(9)7-3-4/h2-3H,1H3,(H,7,9)

InChIKey

QAINEQVHSHARMD-UHFFFAOYSA-N

LogP

1.52700

Complexity

272

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-methyl-3-nitro-2(1h)-pyridinone
2-Hydroxy-3-nitro-5-picoline (2-Hydroxy-5-methyl-3-nitropyridine)
AKOS002137240
AKOS015841962
PS-5450
3-(nitro)-5-methylpyridin-2-ol
AF-753/00294046
SR-01000581601-1
H1483
FT-0655942
5-methyl-3-nitro-1H-pyridin-2-one
SMR000314798
SCHEMBL131620
DTXSID90323215
AB10657
CS-10714
AM62346
2-hydroxy-3-nitro-5-methylpyridine
5-Methyl-3-nitro-2-pyridinol
cid_345643
QAINEQVHSHARMD-UHFFFAOYSA-N
5-methyl-3-nitro-1H-pyridone
NSC403369
5-methyl-3-nitropyridin-2-ol
HMS2772H09
2-Hydroxy-3-nitro-5-picoline
6-Hydroxy-5-nitro-3-picoline
BDBM46498
5-Methyl-3-nitro-2(1H)-pyridone
NSC-403369
5-Methyl-3-nitropyridin-2-ol;2-Hydroxy-3-nitro-5-methylpyridine

MDL Number

MFCD02070021

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4)?

5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4) is a crystalline solid with a molecular weight of approximately 188.11 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. Chemically, it is relatively stable but can undergo nitro reduction, making it important in synthetic chemistry and pharmaceutical applications.

How is 5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4) typically synthesized?

5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4) can be synthesized via nitration of 3-methyl-2(1H)-pyridone using nitric acid and sulfuric acid as the nitration reagents. The process typically involves careful temperature control and the use of a catalyst to enhance yield and selectivity.

What industries use 5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4)?

5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer and sensor industries for its unique chemical properties and reactivity.

What precautions should be taken when handling 5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4)?

When handling 5-Methyl-3-nitro-2(1H)-pyridinone (CAS: 7464-14-4), ensure the use of appropriate personal protective equipment (PPE), including gloves and safety goggles. Store it in a cool, dry place, away from heat sources and incompatible materials. Always work in a well-ventilated area or fume hood to minimize inhalation risk. Refer to the safety data sheet (SDS) for detailed information on handling and disposal.