1,3-Thiazole-5-carboxamide

Basic Information

View in Editor

CAS Number

74411-19-1

Molecular Formula

C4H4N2OS

Molecular Weight

128.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

SMILES

View in Editor

C1=C(SC=N1)C(=O)N

InChI

InChI=1S/C4H4N2OS/c5-4(7)3-1-6-2-8-3/h1-2H,(H2,5,7)

InChIKey

GGNIKGLUPSHSBV-UHFFFAOYSA-N

LogP

0.242

Topological Polar Surface Area

55.980000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

106

Synonyms & References

English

FT-0703496
1,3-thiazole-5-carboxamide
Thiazole-5-carboxamide, AldrichCPR
DTXSID20225410
J-524915
NS00037620
SCHEMBL954218
EN300-72327
SY065656
Q27225540
MFCD06797205
D79735
EINECS 277-861-6
Thiazole-5-carboxylic acid amide
74411-19-1
A19589
UNII-Q6YS0A8KQE
Z741560256
GGNIKGLUPSHSBV-UHFFFAOYSA-N
Thiazole-5-carboxamide
AKOS006221412
5-Thiazolecarboxamide
CHEBI:132332
Q6YS0A8KQE
CS-0259104
5-Carbamyltiazol
Thiazol-5-carbamid
thiazole-5-carboxylic acid amide

MDL Number

MFCD06797205

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 1,3-Thiazole-5-carboxamide (CAS: 74411-19-1)?

1,3-Thiazole-5-carboxamide (CAS: 74411-19-1) is a colorless solid with a melting point of 178-179°C. It has a molecular weight of 145.15 g/mol and is slightly soluble in water. It is highly reactive towards nucleophiles and can undergo substitutions at the nitrogen atom.

How is 1,3-Thiazole-5-carboxamide (CAS: 74411-19-1) typically synthesized?

1,3-Thiazole-5-carboxamide (CAS: 74411-19-1) can be synthesized by the reaction of 1,3-thiazole-5-carboxylic acid with an amine, usually in the presence of a catalytic amount of a compatible base. The reaction is typically carried out in an inert solvent and yields a high percentage of the product.

What industries use 1,3-Thiazole-5-carboxamide (CAS: 74411-19-1)?

1,3-Thiazole-5-carboxamide (CAS: 74411-19-1) is primarily used in the pharmaceutical industry as a starting material for various drug synthesis. It is also utilized in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 1,3-Thiazole-5-carboxamide (CAS: 74411-19-1)?

When handling 1,3-Thiazole-5-carboxamide (CAS: 74411-19-1), it should be done in a well-ventilated area or under a fume hood. Protective equipment such as gloves and safety goggles should be worn. Spills should be cleaned up with appropriate absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.