(RS)-AMPA | CAS No. 74341-63-2

(RS)-AMPA

Basic Information

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CAS Number

74341-63-2

Molecular Formula

C7H10N2O4

Molecular Weight

186.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

240-252 °C

Boiling Point

320.64°C (rough estimate)

Density

1.3962 (rough estimate)

Water Solubility

Soluble in warm water at 1mg/ml. Also soluble in 0.1M NaOH or 0.1M HCl at approximately 4mg/ml. Soluble in DMSO at 4mg/ml

Solubility

H2O: 1 mg/mL warm

Refractive Index

1.4880 (estimate)

SMILES

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OC(=O)C(Cc1c(C)onc1O)N

InChI

InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)

InChIKey

UUDAMDVQRQNNHZ-UHFFFAOYSA-N

LogP

-0.35698

Topological Polar Surface Area

109.58 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

284

Safety Information

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Stability

Store in freezer at -20°C

Synonyms & References

English

(RS)-AMPA
(R,S)-2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPIONIC ACID
(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
AMPA
(+/-)-2-dipropylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene
(+/-)-2-dirpopylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene
(2R)-(+)-8-hydroxy-2-(di-n-propylamino)tetralin
2-dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene
8-hydroxy-2-(di-n-propylamino)tetralin
8-OH-2-(di-n-propylamino)-1,2,3,4-tetrahydronaphthalene
(+/-)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

MDL Number

MFCD00213388

Customs Code

2934999090

FAQ

What is (RS)-AMPA (CAS: 74341-63-2)?

(RS)-AMPA, or (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, is a glutamate receptor agonist. It is a colorless crystalline compound with a molecular formula of C5H9NO3. It is known for its role as an excitatory neurotransmitter modulator in the central nervous system.

What are the main uses of (RS)-AMPA (CAS: 74341-63-2)?

(RS)-AMPA is primarily used as a research tool to study glutamate receptors. It is also used in neuroscience to model neurological disorders and to develop potential therapeutics for neurological diseases such as Alzheimer's and Parkinson's. In addition, it can be used in pharmacological assays to understand receptor dynamics.

Is (RS)-AMPA (CAS: 74341-63-2) safe?

(RS)-AMPA requires caution due to its potential neurotoxic effects. It should be handled under appropriate laboratory conditions, such as in a fume hood, and appropriate personal protective equipment (PPE) should be worn. It is classified as a hazardous material and should be stored in a secure location to prevent accidental exposure.

How should (RS)-AMPA (CAS: 74341-63-2) be stored?

(RS)-AMPA should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should be maintained between 2°C and 8°C to ensure stability and safety.