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(+/-)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid(CAS: 74341-63-2)

(+/-)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
CAS Number

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Basic Information

Molecular Formula
C7H10N2O4
Molecular Weight
186.17 g/mol

Physical Properties

Melting Point
240-252 °C
Boiling Point
320.64°C (rough estimate)
Density
1.3962 (rough estimate)
Water Solubility
Soluble in warm water at 1mg/ml. Also soluble in 0.1M NaOH or 0.1M HCl at approximately 4mg/ml. Soluble in DMSO at 4mg/ml

Chemical Identifiers

SMILES
OC(=O)C(Cc1c(C)onc1O)N
InChIKey
UUDAMDVQRQNNHZ-UHFFFAOYSA-N

Database References

MDL Number
MFCD00213388

FAQ

(RS)-AMPA, or (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, is a glutamate receptor agonist. It is a colorless crystalline compound with a molecular formula of C5H9NO3. It is known for its role as an excitatory neurotransmitter modulator in the central nervous system.
(RS)-AMPA is primarily used as a research tool to study glutamate receptors. It is also used in neuroscience to model neurological disorders and to develop potential therapeutics for neurological diseases such as Alzheimer's and Parkinson's. In addition, it can be used in pharmacological assays to understand receptor dynamics.
(RS)-AMPA requires caution due to its potential neurotoxic effects. It should be handled under appropriate laboratory conditions, such as in a fume hood, and appropriate personal protective equipment (PPE) should be worn. It is classified as a hazardous material and should be stored in a secure location to prevent accidental exposure.
(RS)-AMPA should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should be maintained between 2°C and 8°C to ensure stability and safety.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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